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ERK-Mediated Loss of miR-199a-3p and Induction of EGR1 Act as a "Toggle Switch" of GBM Cell Dedifferentiation into NANOG- and OCT4-Positive Cells.
Almairac F, Turchi L, Sakakini N, Debruyne DN, Elkeurti S, Gjernes E, Polo B, Bianchini L, Fontaine D, Paquis P, Chneiweiss H, Junier MP, Verrando P, Burel-Vandenbos F, Virolle T. Almairac F, et al. Among authors: paquis p. Cancer Res. 2020 Aug 15;80(16):3236-3250. doi: 10.1158/0008-5472.CAN-19-0855. Epub 2020 May 4. Cancer Res. 2020. PMID: 32366479
DOCK4 promotes loss of proliferation in glioblastoma progenitor cells through nuclear beta-catenin accumulation and subsequent miR-302-367 cluster expression.
Debruyne DN, Turchi L, Burel-Vandenbos F, Fareh M, Almairac F, Virolle V, Figarella-Branger D, Baeza-Kallee N, Lagadec P, Kubiniek V, Paquis P, Fontaine D, Junier MP, Chneiweiss H, Virolle T. Debruyne DN, et al. Among authors: paquis p. Oncogene. 2018 Jan 11;37(2):241-254. doi: 10.1038/onc.2017.323. Epub 2017 Sep 18. Oncogene. 2018. PMID: 28925399
Bevacizumab: Is the lower the better for glioblastoma patients in progression?
Sirven-Villaros L, Bourg V, Suissa L, Mondot L, Almairac F, Fontaine D, Paquis P, Burel-VandenBos F, Frenay M, Thomas P, Lebrun-Frenay C. Sirven-Villaros L, et al. Among authors: paquis p. Bull Cancer. 2018 Dec;105(12):1135-1146. doi: 10.1016/j.bulcan.2018.07.010. Epub 2018 Oct 6. Bull Cancer. 2018. PMID: 30301554
The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network.
Fareh M, Turchi L, Virolle V, Debruyne D, Almairac F, de-la-Forest Divonne S, Paquis P, Preynat-Seauve O, Krause KH, Chneiweiss H, Virolle T. Fareh M, et al. Among authors: paquis p. Cell Death Differ. 2012 Feb;19(2):232-44. doi: 10.1038/cdd.2011.89. Epub 2011 Jul 1. Cell Death Differ. 2012. PMID: 21720384 Free PMC article.
[Genetic diseases and glioblastomas].
Almairac F, Frenay M, Paquis P. Almairac F, et al. Among authors: paquis p. Neurochirurgie. 2010 Dec;56(6):455-8. doi: 10.1016/j.neuchi.2010.07.007. Epub 2010 Sep 24. Neurochirurgie. 2010. PMID: 20869734 Review. French.
118 results