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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Schepens B, van Schie L, Nerinckx W, Roose K, Van Breedam W, Fijalkowska D, Devos S, Weyts W, De Cae S, Vanmarcke S, Lonigro C, Eeckhaut H, Van Herpe D, Borloo J, Oliveira AF, Catani JPP, Creytens S, De Vlieger D, Michielsen G, Marchan JCZ, Moschonas GD, Rossey I, Sedeyn K, Van Hecke A, Zhang X, Langendries L, Jacobs S, Ter Horst S, Seldeslachts L, Liesenborghs L, Boudewijns R, Thibaut HJ, Dallmeier K, Velde GV, Weynand B, Beer J, Schnepf D, Ohnemus A, Remory I, Foo CS, Abdelnabi R, Maes P, Kaptein SJF, Rocha-Pereira J, Jochmans D, Delang L, Peelman F, Staeheli P, Schwemmle M, Devoogdt N, Tersago D, Germani M, Heads J, Henry A, Popplewell A, Ellis M, Brady K, Turner A, Dombrecht B, Stortelers C, Neyts J, Callewaert N, Saelens X. Schepens B, et al. Among authors: peelman f. Sci Transl Med. 2021 Nov 24;13(621):eabi7826. doi: 10.1126/scitranslmed.abi7826. Epub 2021 Nov 24. Sci Transl Med. 2021. PMID: 34609205 Free PMC article.
Structural basis of the proinflammatory signaling complex mediated by TSLP.
Verstraete K, van Schie L, Vyncke L, Bloch Y, Tavernier J, Pauwels E, Peelman F, Savvides SN. Verstraete K, et al. Among authors: peelman f. Nat Struct Mol Biol. 2014 Apr;21(4):375-82. doi: 10.1038/nsmb.2794. Epub 2014 Mar 16. Nat Struct Mol Biol. 2014. PMID: 24632570
Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression.
Desmet SJ, Thommis J, Vanderhaeghen T, Vandenboorn EMF, Clarisse D, Li Y, Timmermans S, Fijalkowska D, Ratman D, Van Hamme E, De Cauwer L, Staels B, Brunsveld L, Peelman F, Libert C, Tavernier J, De Bosscher K. Desmet SJ, et al. Among authors: peelman f. Mol Metab. 2024 Apr 15;84:101938. doi: 10.1016/j.molmet.2024.101938. Online ahead of print. Mol Metab. 2024. PMID: 38631478 Free PMC article.
Deep mutational scanning of proteins in mammalian cells.
Maes S, Deploey N, Peelman F, Eyckerman S. Maes S, et al. Among authors: peelman f. Cell Rep Methods. 2023 Nov 20;3(11):100641. doi: 10.1016/j.crmeth.2023.100641. Epub 2023 Nov 13. Cell Rep Methods. 2023. PMID: 37963462 Free PMC article. Review.
89 results