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Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.
Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Among authors: priestnall sl. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.
Type I interferons drive MAIT cell functions against bacterial pneumonia.
López-Rodríguez JC, Hancock SJ, Li K, Crotta S, Barrington C, Suárez-Bonnet A, Priestnall SL, Aubé J, Wack A, Klenerman P, Bengoechea JA, Barral P. López-Rodríguez JC, et al. Among authors: priestnall sl. J Exp Med. 2023 Oct 2;220(10):e20230037. doi: 10.1084/jem.20230037. Epub 2023 Jul 26. J Exp Med. 2023. PMID: 37516912 Free PMC article.
Endothelial AHR activity prevents lung barrier disruption in viral infection.
Major J, Crotta S, Finsterbusch K, Chakravarty P, Shah K, Frederico B, D'Antuono R, Green M, Meader L, Suarez-Bonnet A, Priestnall S, Stockinger B, Wack A. Major J, et al. Nature. 2023 Sep;621(7980):813-820. doi: 10.1038/s41586-023-06287-y. Epub 2023 Aug 16. Nature. 2023. PMID: 37587341 Free PMC article.
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis.
Moreira-Teixeira L, Stimpson PJ, Stavropoulos E, Hadebe S, Chakravarty P, Ioannou M, Aramburu IV, Herbert E, Priestnall SL, Suarez-Bonnet A, Sousa J, Fonseca KL, Wang Q, Vashakidze S, Rodríguez-Martínez P, Vilaplana C, Saraiva M, Papayannopoulos V, O'Garra A. Moreira-Teixeira L, et al. Among authors: priestnall sl. Nat Commun. 2020 Nov 4;11(1):5566. doi: 10.1038/s41467-020-19412-6. Nat Commun. 2020. PMID: 33149141 Free PMC article.
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis.
Moreira-Teixeira L, Tabone O, Graham CM, Singhania A, Stavropoulos E, Redford PS, Chakravarty P, Priestnall SL, Suarez-Bonnet A, Herbert E, Mayer-Barber KD, Sher A, Fonseca KL, Sousa J, Cá B, Verma R, Haldar P, Saraiva M, O'Garra A. Moreira-Teixeira L, et al. Among authors: priestnall sl. Nat Immunol. 2020 Apr;21(4):464-476. doi: 10.1038/s41590-020-0610-z. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205882 Free PMC article.
130 results