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FHL2 interacts with EGFR to promote glioblastoma growth.
Sun L, Yu S, Xu H, Zheng Y, Lin J, Wu M, Wang J, Wang A, Lan Q, Furnari F, Cavenee W, Purow B, Li M. Sun L, et al. Among authors: purow b. Oncogene. 2018 Mar;37(10):1386-1398. doi: 10.1038/s41388-017-0068-0. Epub 2018 Jan 11. Oncogene. 2018. PMID: 29321665 Free PMC article.
CDK4/6 inhibition is more active against the glioblastoma proneural subtype.
Li M, Xiao A, Floyd D, Olmez I, Lee J, Godlewski J, Bronisz A, Bhat KPL, Sulman EP, Nakano I, Purow B. Li M, et al. Among authors: purow b. Oncotarget. 2017 Jul 21;8(33):55319-55331. doi: 10.18632/oncotarget.19429. eCollection 2017 Aug 15. Oncotarget. 2017. PMID: 28903422 Free PMC article.
Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B. Olmez I, et al. Among authors: purow b. Neuro Oncol. 2018 Jan 22;20(2):192-202. doi: 10.1093/neuonc/nox119. Neuro Oncol. 2018. PMID: 29048560 Free PMC article.
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes.
Li Y, Guessous F, Zhang Y, Dipierro C, Kefas B, Johnson E, Marcinkiewicz L, Jiang J, Yang Y, Schmittgen TD, Lopes B, Schiff D, Purow B, Abounader R. Li Y, et al. Among authors: purow b. Cancer Res. 2009 Oct 1;69(19):7569-76. doi: 10.1158/0008-5472.CAN-09-0529. Epub 2009 Sep 22. Cancer Res. 2009. PMID: 19773441 Free PMC article.
microRNA-34a is tumor suppressive in brain tumors and glioma stem cells.
Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D, Purow B, Abounader R. Guessous F, et al. Among authors: purow b. Cell Cycle. 2010 Mar 15;9(6):1031-6. doi: 10.4161/cc.9.6.10987. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20190569 Free PMC article.
88 results