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A variant in FTO shows association with melanoma risk not due to BMI.
Nat Genet. 2013 Apr;45(4):428-32, 432e1. doi: 10.1038/ng.2571. Epub 2013 Mar 3.
Nat Genet. 2013.
PMID: 23455637
Free PMC article.
Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk.
Liu H, Wang LE, Liu Z, Chen WV, Amos CI, Lee JE; Q-MEGA and AMFS Investigators; GenoMEL Investigators; Iles MM, Law MH, Barrett JH, Montgomery GW, Taylor JC, MacGregor S, Cust AE, Newton Bishop JA, Hayward NK, Bishop DT, Mann GJ, Affleck P, Wei Q.
Liu H, et al.
Carcinogenesis. 2013 Apr;34(4):885-92. doi: 10.1093/carcin/bgs407. Epub 2013 Jan 4.
Carcinogenesis. 2013.
PMID: 23291271
Free PMC article.
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Most common 'sporadic' cancers have a significant germline genetic component.
Lu Y, Ek WE, Whiteman D, Vaughan TL, Spurdle AB, Easton DF, Pharoah PD, Thompson DJ, Dunning AM, Hayward NK, Chenevix-Trench G; Q-MEGA and AMFS Investigators; ANECS-SEARCH; UKOPS-SEARCH; BEACON Consortium; Macgregor S.
Lu Y, et al.
Hum Mol Genet. 2014 Nov 15;23(22):6112-8. doi: 10.1093/hmg/ddu312. Epub 2014 Jun 18.
Hum Mol Genet. 2014.
PMID: 24943595
Free PMC article.
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Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk.
Law MH, Montgomery GW, Brown KM, Martin NG, Mann GJ, Hayward NK, MacGregor S; Q-MEGA and AMFS Investigators.
Law MH, et al.
J Invest Dermatol. 2012 Feb;132(2):485-7. doi: 10.1038/jid.2011.322. Epub 2011 Oct 13.
J Invest Dermatol. 2012.
PMID: 21993562
Free PMC article.
No abstract available.
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