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Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition.
Kleinpeter P, Fend L, Thioudellet C, Geist M, Sfrontato N, Koerper V, Fahrner C, Schmitt D, Gantzer M, Remy-Ziller C, Brandely R, Villeval D, Rittner K, Silvestre N, Erbs P, Zitvogel L, Quéméneur E, Préville X, Marchand JB. Kleinpeter P, et al. Among authors: quemeneur e. Oncoimmunology. 2016 Sep 9;5(10):e1220467. doi: 10.1080/2162402X.2016.1220467. eCollection 2016. Oncoimmunology. 2016. PMID: 27853644 Free PMC article.
Patient-Derived Tumoroid for the Prediction of Radiotherapy and Chemotherapy Responses in Non-Small-Cell Lung Cancer.
Nounsi A, Seitlinger J, Ponté C, Demiselle J, Idoux-Gillet Y, Pencreach E, Beau-Faller M, Lindner V, Balloul JM, Quemeneur E, Burckel H, Noël G, Olland A, Fioretti F, Falcoz PE, Benkirane-Jessel N, Hua G. Nounsi A, et al. Among authors: quemeneur e. Biomedicines. 2023 Jun 26;11(7):1824. doi: 10.3390/biomedicines11071824. Biomedicines. 2023. PMID: 37509464 Free PMC article.
Sequential administration of MVA-based vaccines and PD-1/PD-L1-blocking antibodies confers measurable benefits on tumor growth and survival: Preclinical studies with MVA-βGal and MVA-MUC1 (TG4010) in a murine tumor model.
Remy-Ziller C, Thioudellet C, Hortelano J, Gantzer M, Nourtier V, Claudepierre MC, Sansas B, Préville X, Bendjama K, Quemeneur E, Rittner K. Remy-Ziller C, et al. Among authors: quemeneur e. Hum Vaccin Immunother. 2018 Jan 2;14(1):140-145. doi: 10.1080/21645515.2017.1373921. Epub 2017 Oct 18. Hum Vaccin Immunother. 2018. PMID: 28925793 Free PMC article.
Cowpox Virus: A New and Armed Oncolytic Poxvirus.
Ricordel M, Foloppe J, Pichon C, Sfrontato N, Antoine D, Tosch C, Cochin S, Cordier P, Quemeneur E, Camus-Bouclainville C, Bertagnoli S, Erbs P. Ricordel M, et al. Among authors: quemeneur e. Mol Ther Oncolytics. 2017 Aug 24;7:1-11. doi: 10.1016/j.omto.2017.08.003. eCollection 2017 Dec 15. Mol Ther Oncolytics. 2017. PMID: 28951885 Free PMC article.
Oncolytic properties of non-vaccinia poxviruses.
Ricordel M, Foloppe J, Pichon C, Findeli A, Tosch C, Cordier P, Cochin S, Quémeneur E, Camus-Bouclainville C, Bertagnoli S, Erbs P. Ricordel M, et al. Among authors: quemeneur e. Oncotarget. 2018 Nov 13;9(89):35891-35906. doi: 10.18632/oncotarget.26288. eCollection 2018 Nov 13. Oncotarget. 2018. PMID: 30542506 Free PMC article.
By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1.
Kleinpeter P, Remy-Ziller C, Winter E, Gantzer M, Nourtier V, Kempf J, Hortelano J, Schmitt D, Schultz H, Geist M, Brua C, Hoffmann C, Schlesinger Y, Villeval D, Thioudellet C, Erbs P, Foloppe J, Silvestre N, Fend L, Quemeneur E, Marchand JB. Kleinpeter P, et al. Among authors: quemeneur e. J Virol. 2019 May 15;93(11):e00207-19. doi: 10.1128/JVI.00207-19. Print 2019 Jun 1. J Virol. 2019. PMID: 30918073 Free PMC article.
89 results