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A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.
Dimmock JR, Padmanilayam MP, Puthucode RN, Nazarali AJ, Motaganahalli NL, Zello GA, Quail JW, Oloo EO, Kraatz HB, Prisciak JS, Allen TM, Santos CL, Balzarini J, De Clercq E, Manavathu EK. Dimmock JR, et al. Among authors: quail jw. J Med Chem. 2001 Feb 15;44(4):586-93. doi: 10.1021/jm0002580. J Med Chem. 2001. PMID: 11170648
Cytotoxic 1,4-bis(2-oxo-1-cycloalkylmethylene)benzenes and related compounds.
Dimmock JR, Jha A, Kumar P, Zello GA, Quail JW, Oloo EO, Oucharek JJ, Pasha MK, Seitz D, Sharma RK, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: quail jw. Eur J Med Chem. 2002 Jan;37(1):35-44. doi: 10.1016/s0223-5234(01)01294-6. Eur J Med Chem. 2002. PMID: 11841873
Cytotoxic 1,3-diarylidene-2-tetralones and related compounds.
Dimmock JR, Padmanilyam MP, Zello GA, Quail JW, Oloo EO, Prisciak JS, Kraatz HB, Cherkasov A, Lee JS, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: quail jw. Eur J Med Chem. 2002 Oct;37(10):813-24. doi: 10.1016/s0223-5234(02)01402-2. Eur J Med Chem. 2002. PMID: 12446039
The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2,4-bis(benzylidene)-8-methyl-8-azabicyclo[3.2.1] octan-3-ones and 3,5-bis(benzylidene)-1-methyl-4-piperidones.
Pati HN, Das U, Das S, Bandy B, De Clercq E, Balzarini J, Kawase M, Sakagami H, Quail JW, Stables JP, Dimmock JR. Pati HN, et al. Among authors: quail jw. Eur J Med Chem. 2009 Jan;44(1):54-62. doi: 10.1016/j.ejmech.2008.03.015. Epub 2008 Mar 29. Eur J Med Chem. 2009. PMID: 18468733 Free PMC article.
65 results