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HSP70i is a critical component of the immune response leading to vitiligo.
Mosenson JA, Zloza A, Klarquist J, Barfuss AJ, Guevara-Patino JA, Poole IC. Mosenson JA, et al. Pigment Cell Melanoma Res. 2012 Jan;25(1):88-98. doi: 10.1111/j.1755-148X.2011.00916.x. Epub 2011 Nov 14. Pigment Cell Melanoma Res. 2012. PMID: 21978301 Free PMC article.
HSP70i accelerates depigmentation in a mouse model of autoimmune vitiligo.
Denman CJ, McCracken J, Hariharan V, Klarquist J, Oyarbide-Valencia K, Guevara-Patiño JA, Le Poole IC. Denman CJ, et al. J Invest Dermatol. 2008 Aug;128(8):2041-8. doi: 10.1038/jid.2008.45. Epub 2008 Mar 13. J Invest Dermatol. 2008. PMID: 18337834 Free PMC article.
Therapeutic implications of autoimmune vitiligo T cells.
Oyarbide-Valencia K, van den Boorn JG, Denman CJ, Li M, Carlson JM, Hernandez C, Nishimura MI, Das PK, Luiten RM, Le Poole IC. Oyarbide-Valencia K, et al. Autoimmun Rev. 2006 Aug;5(7):486-92. doi: 10.1016/j.autrev.2006.03.012. Epub 2006 May 6. Autoimmun Rev. 2006. PMID: 16920575 Free PMC article. Review.