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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 2
2001 4
2002 5
2003 3
2004 4
2005 2
2007 4
2008 12
2009 11
2010 9
2011 13
2012 17
2013 15
2014 15
2015 19
2016 9
2017 9
2018 1
2019 4
2020 1
2024 0

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145 results

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Page 1
Revisiting the tumorigenesis timeline with a data-driven generative model.
Lahouel K, Younes L, Danilova L, Giardiello FM, Hruban RH, Groopman J, Kinzler KW, Vogelstein B, Geman D, Tomasetti C. Lahouel K, et al. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):857-864. doi: 10.1073/pnas.1914589117. Epub 2019 Dec 27. Proc Natl Acad Sci U S A. 2020. PMID: 31882448 Free PMC article.
Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence.
Tomasetti C, Poling J, Roberts NJ, London NR Jr, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B. Tomasetti C, et al. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20482-20488. doi: 10.1073/pnas.1905722116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548407 Free PMC article.
An analysis of genetic heterogeneity in untreated cancers.
Reiter JG, Baretti M, Gerold JM, Makohon-Moore AP, Daud A, Iacobuzio-Donahue CA, Azad NS, Kinzler KW, Nowak MA, Vogelstein B. Reiter JG, et al. Nat Rev Cancer. 2019 Nov;19(11):639-650. doi: 10.1038/s41568-019-0185-x. Epub 2019 Aug 27. Nat Rev Cancer. 2019. PMID: 31455892 Free PMC article. Review.
Minimal functional driver gene heterogeneity among untreated metastases.
Reiter JG, Makohon-Moore AP, Gerold JM, Heyde A, Attiyeh MA, Kohutek ZA, Tokheim CJ, Brown A, DeBlasio RM, Niyazov J, Zucker A, Karchin R, Kinzler KW, Iacobuzio-Donahue CA, Vogelstein B, Nowak MA. Reiter JG, et al. Science. 2018 Sep 7;361(6406):1033-1037. doi: 10.1126/science.aat7171. Science. 2018. PMID: 30190408 Free PMC article.
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duffy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhoff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taube J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW, Eshleman JR, Vogelstein B, Anders RA, Diaz LA Jr. Le DT, et al. Science. 2017 Jul 28;357(6349):409-413. doi: 10.1126/science.aan6733. Epub 2017 Jun 8. Science. 2017. PMID: 28596308 Free PMC article. Clinical Trial.
A Tunable Brake for HECT Ubiquitin Ligases.
Chen Z, Jiang H, Xu W, Li X, Dempsey DR, Zhang X, Devreotes P, Wolberger C, Amzel LM, Gabelli SB, Cole PA. Chen Z, et al. Mol Cell. 2017 May 4;66(3):345-357.e6. doi: 10.1016/j.molcel.2017.03.020. Mol Cell. 2017. PMID: 28475870 Free PMC article.
145 results