Modulation of multidrug resistance in Chinese hamster cells by liposome-encapsulated doxorubicin.
Thierry AR, Jorgensen TJ, Forst D, Belli JA, Dritschilo A, Rahman A.
Thierry AR, et al. Among authors: rahman a.
Cancer Commun. 1989;1(5):311-6. doi: 10.3727/095535489820874931.
Cancer Commun. 1989.
PMID: 2577154
A Chinese hamster cell line (LZ), selected for multidrug resistance (MDR), exhibits a 3,000-fold resistance to doxorubicin, compared to parental V-79 cells. These drug resistant cells have amplified MDR genes, overexpress P-glycoprotein, and in the presence of doxor …
A Chinese hamster cell line (LZ), selected for multidrug resistance (MDR), exhibits a 3,000-fold resistance to doxorubicin, co …