Richel D - Search Results

1

Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin.

Hulsman N, Medema JP, Bos C, Jongejan A, Leurs R, Smit MJ, de Esch IJ, Richel D, Wijtmans M. Hulsman N, et al. Among authors: richel d. J Med Chem. 2007 May 17;50(10):2424-31. doi: 10.1021/jm061371e. Epub 2007 Apr 19. J Med Chem. 2007. PMID: 17441704

2

Targeting Wnt signaling in colon cancer stem cells.

de Sousa EM, Vermeulen L, Richel D, Medema JP. de Sousa EM, et al. Among authors: richel d. Clin Cancer Res. 2011 Feb 15;17(4):647-53. doi: 10.1158/1078-0432.CCR-10-1204. Epub 2010 Dec 15. Clin Cancer Res. 2011. PMID: 21159886 Review.

3

The developing cancer stem-cell model: clinical challenges and opportunities.

Vermeulen L, de Sousa e Melo F, Richel DJ, Medema JP. Vermeulen L, et al. Lancet Oncol. 2012 Feb;13(2):e83-9. doi: 10.1016/S1470-2045(11)70257-1. Lancet Oncol. 2012. PMID: 22300863 Review.

4

Farnesyl protein transferase inhibition interferes with activation of MAP kinase family members in human peripheral blood monocytes.

Vervenne WL, Bos CL, Rens LS, Peppelenbosch MP, Richel DJ. Vervenne WL, et al. Mol Med. 2002 Dec;8(12):857-62. Mol Med. 2002. PMID: 12606821 Free PMC article.

5

[Cancer stem cells].

Vermeulen L, Verhoeff JJ, Richel DJ, Medema JP. Vermeulen L, et al. Ned Tijdschr Geneeskd. 2009 Feb 14;153(7):286-90. Ned Tijdschr Geneeskd. 2009. PMID: 19291944 Review. Dutch. No abstract available.

6

Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A.

Bos CL, Kodach LL, van den Brink GR, Diks SH, van Santen MM, Richel DJ, Peppelenbosch MP, Hardwick JC. Bos CL, et al. Among authors: richel dj. Oncogene. 2006 Oct 19;25(49):6447-56. doi: 10.1038/sj.onc.1209658. Epub 2006 Jul 31. Oncogene. 2006. PMID: 16878161

7

Prostanoids and prostanoid receptors in signal transduction.

Bos CL, Richel DJ, Ritsema T, Peppelenbosch MP, Versteeg HH. Bos CL, et al. Int J Biochem Cell Biol. 2004 Jul;36(7):1187-205. doi: 10.1016/j.biocel.2003.08.006. Int J Biochem Cell Biol. 2004. PMID: 15109566 Review.

8

Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity.

Bos CL, Diks SH, Hardwick JC, Walburg KV, Peppelenbosch MP, Richel DJ. Bos CL, et al. Carcinogenesis. 2006 Dec;27(12):2371-82. doi: 10.1093/carcin/bgl071. Epub 2006 May 25. Carcinogenesis. 2006. PMID: 16728434

9

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.

de Jong JH, Rodermond HM, Zimberlin CD, Lascano V, De Sousa E Melo F, Richel DJ, Medema JP, Vermeulen L. de Jong JH, et al. Among authors: richel dj. Sci Rep. 2012;2:271. doi: 10.1038/srep00271. Epub 2012 Feb 15. Sci Rep. 2012. PMID: 22355783 Free PMC article.

10

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.

Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Vermeulen L, et al. Nat Cell Biol. 2010 May;12(5):468-76. doi: 10.1038/ncb2048. Epub 2010 Apr 25. Nat Cell Biol. 2010. PMID: 20418870

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