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JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
Pennel KAF, Hatthakarnkul P, Wood CS, Lian GY, Al-Badran SSF, Quinn JA, Legrini A, Inthagard J, Alexander PG, van Wyk H, Kurniawan A, Hashmi U, Gillespie MA, Mills M, Ammar A, Hay J, Andersen D, Nixon C, Rebus S, Chang DK, Kelly C, Harkin A, Graham J, Church D, Tomlinson I, Saunders M, Iveson T, Lannagan TRM, Jackstadt R, Maka N, Horgan PG, Roxburgh CSD, Sansom OJ, McMillan DC, Steele CW, Jamieson NB, Park JH, Roseweir AK, Edwards J. Pennel KAF, et al. Among authors: roseweir ak. J Exp Clin Cancer Res. 2024 Mar 1;43(1):64. doi: 10.1186/s13046-024-02958-4. J Exp Clin Cancer Res. 2024. PMID: 38424636 Free PMC article.
β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer.
Suzuki T, Kilbey A, Casa-Rodríguez N, Lawlor A, Georgakopoulou A, Hayman H, Yin Swe KL, Nordin A, Cantù C, Vantourout P, Ridgway RA, Byrne RM, Chen L, Verzi MP, Gay DM, Gil Vázquez E, Belnoue-Davis HL, Gilroy K, Køstner AH, Kersten C, Thuwajit C, Andersen DK, Wiesheu R, Jandke A, Blyth K, Roseweir AK, Leedham SJ, Dunne PD, Edwards J, Hayday A, Sansom OJ, Coffelt SB. Suzuki T, et al. Among authors: roseweir ak. Cancer Immunol Res. 2023 Aug 3;11(8):1137-1155. doi: 10.1158/2326-6066.CIR-22-0644. Cancer Immunol Res. 2023. PMID: 37309673 Free PMC article.
Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases.
Wood CS, Pennel KAF, Leslie H, Legrini A, Cameron AJ, Melissourgou-Syka L, Quinn JA, van Wyk HC, Hay J, Roseweir AK, Nixon C, Roxburgh CSD, McMillan DC, Biankin AV, Sansom OJ, Horgan PG, Edwards J, Steele CW, Jamieson NB. Wood CS, et al. Among authors: roseweir ak. Cancer Res. 2023 Apr 14;83(8):1329-1344. doi: 10.1158/0008-5472.CAN-22-2794. Cancer Res. 2023. PMID: 37057593 Free PMC article.
CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer.
Pennel KA, Quinn JA, Nixon C, Inthagard J, van Wyk HC, Chang D, Rebus S; GPOL Group; Hay J, Maka NN, Roxburgh CS, Horgan PG, McMillan DC, Park JH, Roseweir AK, Steele CW, Edwards J. Pennel KA, et al. Among authors: roseweir ak. J Pathol Clin Res. 2022 Nov;8(6):509-520. doi: 10.1002/cjp2.290. Epub 2022 Jul 25. J Pathol Clin Res. 2022. PMID: 35879507 Free PMC article.
The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer.
Alexander PG, Matly AAM, Jirapongwattana N, Pennel KAF, van Wyk HC, McMillan DC, Horgan PG, Roxburgh CSD, Thuwajit C, Roseweir AK, Quinn J, Park JH, Edwards J. Alexander PG, et al. Among authors: roseweir ak. Hum Pathol. 2022 Sep;127:1-11. doi: 10.1016/j.humpath.2022.05.012. Epub 2022 May 25. Hum Pathol. 2022. PMID: 35623467 Free article.
Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer.
Al-Badran SS, Grant L, Campo MV, Inthagard J, Pennel K, Quinn J, Konanahalli P, Hayman L, Horgan PG, McMillan DC, Roxburgh CS, Roseweir A, Park JH, Edwards J. Al-Badran SS, et al. Among authors: roseweir a. J Pathol Clin Res. 2021 Mar;7(2):121-134. doi: 10.1002/cjp2.193. Epub 2020 Dec 18. J Pathol Clin Res. 2021. PMID: 33338327 Free PMC article.
Determining the prognostic significance of IKKα in prostate cancer.
Montes M, MacKenzie L, McAllister MJ, Roseweir A, McCall P, Hatziieremia S, Underwood MA, Boyd M, Paul A, Plevin R, MacKay SP, Edwards J. Montes M, et al. Among authors: roseweir a. Prostate. 2020 Oct;80(14):1188-1202. doi: 10.1002/pros.24045. Epub 2020 Jul 21. Prostate. 2020. PMID: 33258506 Free article.
45 results