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CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice.
Olofsson PS, Söderström LA, Wågsäter D, Sheikine Y, Ocaya P, Lang F, Rabu C, Chen L, Rudling M, Aukrust P, Hedin U, Paulsson-Berne G, Sirsjö A, Hansson GK. Olofsson PS, et al. Among authors: soderstrom la. Circulation. 2008 Mar 11;117(10):1292-301. doi: 10.1161/CIRCULATIONAHA.107.699173. Epub 2008 Feb 19. Circulation. 2008. PMID: 18285570
Human genetic evidence for involvement of CD137 in atherosclerosis.
Söderström LÅ, Gertow K, Folkersen L, Sabater-Lleal M, Sundman E, Sheikine Y, Goel A, Baldassarre D, Humphries SE, de Faire U, Watkins H, Tremoli E, Veglia F, Hamsten A, Hansson GK, Olofsson PS. Söderström LÅ, et al. Mol Med. 2014 Oct 14;20(1):456-65. doi: 10.2119/molmed.2014.00004. Mol Med. 2014. PMID: 25032953 Free PMC article.
CD137: A checkpoint regulator involved in atherosclerosis.
Söderström LÅ, Tarnawski L, Olofsson PS. Söderström LÅ, et al. Atherosclerosis. 2018 May;272:66-72. doi: 10.1016/j.atherosclerosis.2018.03.007. Epub 2018 Mar 5. Atherosclerosis. 2018. PMID: 29571029 Review.
Genetic variants of TNFSF4 and risk for carotid artery disease and stroke.
Olofsson PS, Söderström LA, Jern C, Sirsjö A, Ria M, Sundler E, de Faire U, Wiklund PG, Ohrvik J, Hedin U, Paulsson-Berne G, Hamsten A, Eriksson P, Hansson GK. Olofsson PS, et al. Among authors: soderstrom la. J Mol Med (Berl). 2009 Apr;87(4):337-46. doi: 10.1007/s00109-008-0412-5. Epub 2008 Nov 8. J Mol Med (Berl). 2009. PMID: 18998106
Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice.
Kumawat AK, Zegeye MM, Paramel GV, Baumgartner R, Gisterå A, Amegavie O, Hellberg S, Jin H, Caravaca AS, Söderström LÅ, Gudmundsdotter L, Frejd FY, Ljungberg LU, Olofsson PS, Ketelhuth DFJ, Sirsjö A. Kumawat AK, et al. Among authors: soderstrom la. Front Cardiovasc Med. 2022 Feb 24;9:831039. doi: 10.3389/fcvm.2022.831039. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35282365 Free PMC article.
A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis.
Krivospitskaya O, Elmabsout AA, Sundman E, Söderström LA, Ovchinnikova O, Gidlöf AC, Scherbak N, Norata GD, Samnegård A, Törmä H, Abdel-Halim SM, Jansson JH, Eriksson P, Sirsjö A, Olofsson PS. Krivospitskaya O, et al. Among authors: soderstrom la. Mol Med. 2012 May 9;18(1):712-8. doi: 10.2119/molmed.2012.00094. Mol Med. 2012. PMID: 22415012 Free PMC article.