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Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet Respir Med. 2021 Oct;9(10):1141-1153. doi: 10.1016/S2213-2600(21)00097-7. Epub 2021 Apr 16.
Lancet Respir Med. 2021.
PMID: 33872587
Sustained efficacy of mepolizumab in patients with severe chronic rhinosinusitis with nasal polyps: SYNAPSE 24-week treatment-free follow-up.
Desrosiers M, Diamant Z, Castelnuovo P, Hellings PW, Han JK, Peters AT, Silver J, Smith SG, Fuller A, Sousa AR, Chan RH, Gevaert P; SYNAPSE study investigators.
Desrosiers M, et al.
Int Forum Allergy Rhinol. 2024 Jan;14(1):18-31. doi: 10.1002/alr.23219. Epub 2023 Jul 18.
Int Forum Allergy Rhinol. 2024.
PMID: 37345861
Clinical Trial.
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