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UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer.
Sai K, Saeki M, Saito Y, Ozawa S, Katori N, Jinno H, Hasegawa R, Kaniwa N, Sawada J, Komamura K, Ueno K, Kamakura S, Kitakaze M, Kitamura Y, Kamatani N, Minami H, Ohtsu A, Shirao K, Yoshida T, Saijo N. Sai K, et al. Clin Pharmacol Ther. 2004 Jun;75(6):501-15. doi: 10.1016/j.clpt.2004.01.010. Clin Pharmacol Ther. 2004. PMID: 15179405
Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients.
Sai K, Saito Y, Fukushima-Uesaka H, Kurose K, Kaniwa N, Kamatani N, Shirao K, Yamamoto N, Hamaguchi T, Kunitoh H, Ohe Y, Tamura T, Yamada Y, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J. Sai K, et al. Cancer Chemother Pharmacol. 2008 Aug;62(3):529-37. doi: 10.1007/s00280-007-0634-1. Epub 2007 Nov 8. Cancer Chemother Pharmacol. 2008. PMID: 17992531
Genetic variations and frequencies of major haplotypes in SLCO1B1 encoding the transporter OATP1B1 in Japanese subjects: SLCO1B1*17 is more prevalent than *15.
Kim SR, Saito Y, Sai K, Kurose K, Maekawa K, Kaniwa N, Ozawa S, Kamatani N, Shirao K, Yamamoto N, Hamaguchi T, Kunitoh H, Ohe Y, Yamada Y, Tamura T, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J. Kim SR, et al. Among authors: sai k. Drug Metab Pharmacokinet. 2007 Dec;22(6):456-61. doi: 10.2133/dmpk.22.456. Drug Metab Pharmacokinet. 2007. PMID: 18159134 Free article.
310 results