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The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets.
Peacock TP, Goldhill DH, Zhou J, Baillon L, Frise R, Swann OC, Kugathasan R, Penn R, Brown JC, Sanchez-David RY, Braga L, Williamson MK, Hassard JA, Staller E, Hanley B, Osborn M, Giacca M, Davidson AD, Matthews DA, Barclay WS. Peacock TP, et al. Among authors: sanchez david ry. Nat Microbiol. 2021 Jul;6(7):899-909. doi: 10.1038/s41564-021-00908-w. Epub 2021 Apr 27. Nat Microbiol. 2021. PMID: 33907312
ACE2: The Only Thing That Matters?
Sanchez-David RY, Swann OC, Peacock TP, Barclay WS. Sanchez-David RY, et al. Am J Respir Crit Care Med. 2020 Jul 15;202(2):161-163. doi: 10.1164/rccm.202006-2151ED. Am J Respir Crit Care Med. 2020. PMID: 32520592 Free PMC article. No abstract available.
LGP2 binds to PACT to regulate RIG-I- and MDA5-mediated antiviral responses.
Sanchez David RY, Combredet C, Najburg V, Millot GA, Beauclair G, Schwikowski B, Léger T, Camadro JM, Jacob Y, Bellalou J, Jouvenet N, Tangy F, Komarova AV. Sanchez David RY, et al. Sci Signal. 2019 Oct 1;12(601):eaar3993. doi: 10.1126/scisignal.aar3993. Sci Signal. 2019. PMID: 31575732
Identification of RNA partners of viral proteins in infected cells.
Komarova AV, Combredet C, Sismeiro O, Dillies MA, Jagla B, Sanchez David RY, Vabret N, Coppée JY, Vidalain PO, Tangy F. Komarova AV, et al. Among authors: sanchez david ry. RNA Biol. 2013 Jun;10(6):944-56. doi: 10.4161/rna.24453. Epub 2013 Apr 1. RNA Biol. 2013. PMID: 23595062 Free PMC article.
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.
Vabret N, Najburg V, Solovyov A, Gopal R, McClain C, Šulc P, Balan S, Rahou Y, Beauclair G, Chazal M, Varet H, Legendre R, Sismeiro O, Sanchez David RY, Chauveau L, Jouvenet N, Markowitz M, van der Werf S, Schwartz O, Tangy F, Bhardwaj N, Greenbaum BD, Komarova AV. Vabret N, et al. Among authors: sanchez david ry. iScience. 2022 Jun 11;25(7):104599. doi: 10.1016/j.isci.2022.104599. eCollection 2022 Jul 15. iScience. 2022. PMID: 35789859 Free PMC article.
Mammalian antiviral RNAi is on the move.
Schierhorn KL, Sanchez-David RY, Maillard PV. Schierhorn KL, et al. Among authors: sanchez david ry. EMBO J. 2022 Jun 1;41(11):e111210. doi: 10.15252/embj.2022111210. Epub 2022 Apr 26. EMBO J. 2022. PMID: 35471636 Free PMC article.
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