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COVID-19 and emerging viral infections: The case for interferon lambda.
Prokunina-Olsson L, Alphonse N, Dickenson RE, Durbin JE, Glenn JS, Hartmann R, Kotenko SV, Lazear HM, O'Brien TR, Odendall C, Onabajo OO, Piontkivska H, Santer DM, Reich NC, Wack A, Zanoni I. Prokunina-Olsson L, et al. Among authors: santer dm. J Exp Med. 2020 May 4;217(5):e20200653. doi: 10.1084/jem.20200653. J Exp Med. 2020. PMID: 32289152 Free PMC article.
Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells.
Santer DM, Minty GES, Golec DP, Lu J, May J, Namdar A, Shah J, Elahi S, Proud D, Joyce M, Tyrrell DL, Houghton M. Santer DM, et al. PLoS Pathog. 2020 Apr 30;16(4):e1008515. doi: 10.1371/journal.ppat.1008515. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32353085 Free PMC article.
Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2.
Onabajo OO, Banday AR, Yan W, Obajemu A, Stanifer ML, Santer DM, Florez-Vargas O, Piontkivska H, Vargas J, Kee C, Tyrrell DLJ, Mendoza JL, Boulant S, Prokunina-Olsson L. Onabajo OO, et al. Among authors: santer dm. bioRxiv [Preprint]. 2020 Jul 20:2020.07.19.210955. doi: 10.1101/2020.07.19.210955. bioRxiv. 2020. PMID: 32743577 Free PMC article. Updated. Preprint.
Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor.
Onabajo OO, Banday AR, Stanifer ML, Yan W, Obajemu A, Santer DM, Florez-Vargas O, Piontkivska H, Vargas JM, Ring TJ, Kee C, Doldan P, Tyrrell DL, Mendoza JL, Boulant S, Prokunina-Olsson L. Onabajo OO, et al. Among authors: santer dm. Nat Genet. 2020 Dec;52(12):1283-1293. doi: 10.1038/s41588-020-00731-9. Epub 2020 Oct 19. Nat Genet. 2020. PMID: 33077916 Free PMC article.
Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial.
Feld JJ, Kandel C, Biondi MJ, Kozak RA, Zahoor MA, Lemieux C, Borgia SM, Boggild AK, Powis J, McCready J, Tan DHS, Chan T, Coburn B, Kumar D, Humar A, Chan A, O'Neil B, Noureldin S, Booth J, Hong R, Smookler D, Aleyadeh W, Patel A, Barber B, Casey J, Hiebert R, Mistry H, Choong I, Hislop C, Santer DM, Lorne Tyrrell D, Glenn JS, Gehring AJ, Janssen HLA, Hansen BE. Feld JJ, et al. Among authors: santer dm. Lancet Respir Med. 2021 May;9(5):498-510. doi: 10.1016/S2213-2600(20)30566-X. Epub 2021 Feb 5. Lancet Respir Med. 2021. PMID: 33556319 Free PMC article. Clinical Trial.
Characterization of Monoclonal Antibodies to Measure Cell Surface Protein Levels of Human Interferon-Lambda Receptor 1.
de Weerd NA, Ogungbola O, Liu X, Matthews AY, Ismail A, Vivian JP, Lim SS, Tyrrell DL, Putcha N, Skawinski M, Dickensheets H, Lavoie TB, Donnelly RP, Hertzog PJ, Santer DM. de Weerd NA, et al. Among authors: santer dm. J Interferon Cytokine Res. 2023 Sep;43(9):403-413. doi: 10.1089/jir.2023.0040. Epub 2023 Jul 27. J Interferon Cytokine Res. 2023. PMID: 37499093
41 results