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Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract.
Dev Cell. 2020 Jun 8;53(5):514-529.e3. doi: 10.1016/j.devcel.2020.05.012. Epub 2020 May 16.
Dev Cell. 2020.
PMID: 32425701
Free PMC article.
Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials.
Lin A, Giuliano CJ, Palladino A, John KM, Abramowicz C, Yuan ML, Sausville EL, Lukow DA, Liu L, Chait AR, Galluzzo ZC, Tucker C, Sheltzer JM.
Lin A, et al. Among authors: sausville el.
Sci Transl Med. 2019 Sep 11;11(509):eaaw8412. doi: 10.1126/scitranslmed.aaw8412.
Sci Transl Med. 2019.
PMID: 31511426
Free PMC article.
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Aneuploidy as a promoter and suppressor of malignant growth.
Vasudevan A, Schukken KM, Sausville EL, Girish V, Adebambo OA, Sheltzer JM.
Vasudevan A, et al. Among authors: sausville el.
Nat Rev Cancer. 2021 Feb;21(2):89-103. doi: 10.1038/s41568-020-00321-1. Epub 2021 Jan 11.
Nat Rev Cancer. 2021.
PMID: 33432169
Review.
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Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies.
Lukow DA, Sausville EL, Suri P, Chunduri NK, Wieland A, Leu J, Smith JC, Girish V, Kumar AA, Kendall J, Wang Z, Storchova Z, Sheltzer JM.
Lukow DA, et al. Among authors: sausville el.
Dev Cell. 2021 Sep 13;56(17):2427-2439.e4. doi: 10.1016/j.devcel.2021.07.009. Epub 2021 Aug 4.
Dev Cell. 2021.
PMID: 34352222
Free PMC article.
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Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding.
Ghosh A, Girish V, Yuan ML, Coakley RD, Wrennall JA, Alexis NE, Sausville EL, Vasudevan A, Chait AR, Sheltzer JM, Tarran R.
Ghosh A, et al. Among authors: sausville el.
Am J Respir Crit Care Med. 2022 Jan 1;205(1):129-133. doi: 10.1164/rccm.202106-1377LE.
Am J Respir Crit Care Med. 2022.
PMID: 34748720
Free PMC article.
No abstract available.
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Oncogene-like addiction to aneuploidy in human cancers.
Girish V, Lakhani AA, Thompson SL, Scaduto CM, Brown LM, Hagenson RA, Sausville EL, Mendelson BE, Kandikuppa PK, Lukow DA, Yuan ML, Stevens EC, Lee SN, Schukken KM, Akalu SM, Vasudevan A, Zou C, Salovska B, Li W, Smith JC, Taylor AM, Martienssen RA, Liu Y, Sun R, Sheltzer JM.
Girish V, et al. Among authors: sausville el.
Science. 2023 Aug 25;381(6660):eadg4521. doi: 10.1126/science.adg4521. Epub 2023 Aug 25.
Science. 2023.
PMID: 37410869
Free PMC article.
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Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor.
Bhattacharjee D, Bakar J, Chitnis SP, Sausville EL, Ashtekar KD, Mendelson BE, Long K, Smith JC, Heppner DE, Sheltzer JM.
Bhattacharjee D, et al. Among authors: sausville el.
Cell Chem Biol. 2023 Oct 19;30(10):1211-1222.e5. doi: 10.1016/j.chembiol.2023.09.013. Epub 2023 Oct 11.
Cell Chem Biol. 2023.
PMID: 37827156
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Oncogene-like addiction to aneuploidy in human cancers.
Girish V, Lakhani AA, Scaduto CM, Thompson SL, Brown LM, Hagenson RA, Sausville EL, Mendelson BE, Lukow DA, Yuan ML, Kandikuppa PK, Stevens EC, Lee SN, Salovska B, Li W, Smith JC, Taylor AM, Martienssen RA, Liu Y, Sun R, Sheltzer JM.
Girish V, et al. Among authors: sausville el.
bioRxiv [Preprint]. 2023 Jan 10:2023.01.09.523344. doi: 10.1101/2023.01.09.523344.
bioRxiv. 2023.
PMID: 36711674
Free PMC article.
Updated.
Preprint.
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