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The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption.
van der Eerden BC, Hoenderop JG, de Vries TJ, Schoenmaker T, Buurman CJ, Uitterlinden AG, Pols HA, Bindels RJ, van Leeuwen JP. van der Eerden BC, et al. Among authors: schoenmaker t. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17507-12. doi: 10.1073/pnas.0505789102. Epub 2005 Nov 16. Proc Natl Acad Sci U S A. 2005. PMID: 16291808 Free PMC article.
Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity.
Perez-Amodio S, Jansen DC, Schoenmaker T, Vogels IM, Reinheckel T, Hayman AR, Cox TM, Saftig P, Beertsen W, Everts V. Perez-Amodio S, et al. Among authors: schoenmaker t. Calcif Tissue Int. 2006 Oct;79(4):245-54. doi: 10.1007/s00223-005-0289-z. Epub 2006 Oct 10. Calcif Tissue Int. 2006. PMID: 17033726
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