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Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists.
Ieremias L, Kaspersen MH, Manandhar A, Schultz-Knudsen K, Vrettou CI, Pokhrel R, Heidtmann CV, Jenkins L, Kanellou C, Marsango S, Li Y, Bräuner-Osborne H, Rexen Ulven E, Milligan G, Ulven T. Ieremias L, et al. Among authors: schultz knudsen k. J Med Chem. 2024 Mar 14;67(5):3542-3570. doi: 10.1021/acs.jmedchem.3c01923. Epub 2024 Feb 21. J Med Chem. 2024. PMID: 38381650
Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.
Valentini A, Schultz-Knudsen K, Højgaard Hansen A, Tsakoumagkou A, Jenkins L, Christensen HB, Manandhar A, Milligan G, Ulven T, Rexen Ulven E. Valentini A, et al. Among authors: schultz knudsen k. J Med Chem. 2023 May 11;66(9):6105-6121. doi: 10.1021/acs.jmedchem.2c01935. Epub 2023 May 2. J Med Chem. 2023. PMID: 37129317 Free PMC article.
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.
Abildgaard AB, Stein A, Nielsen SV, Schultz-Knudsen K, Papaleo E, Shrikhande A, Hoffmann ER, Bernstein I, Gerdes AM, Takahashi M, Ishioka C, Lindorff-Larsen K, Hartmann-Petersen R. Abildgaard AB, et al. Among authors: schultz knudsen k. Elife. 2019 Nov 7;8:e49138. doi: 10.7554/eLife.49138. Elife. 2019. PMID: 31697235 Free PMC article.