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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Schepens B, van Schie L, Nerinckx W, Roose K, Van Breedam W, Fijalkowska D, Devos S, Weyts W, De Cae S, Vanmarcke S, Lonigro C, Eeckhaut H, Van Herpe D, Borloo J, Oliveira AF, Catani JPP, Creytens S, De Vlieger D, Michielsen G, Marchan JCZ, Moschonas GD, Rossey I, Sedeyn K, Van Hecke A, Zhang X, Langendries L, Jacobs S, Ter Horst S, Seldeslachts L, Liesenborghs L, Boudewijns R, Thibaut HJ, Dallmeier K, Velde GV, Weynand B, Beer J, Schnepf D, Ohnemus A, Remory I, Foo CS, Abdelnabi R, Maes P, Kaptein SJF, Rocha-Pereira J, Jochmans D, Delang L, Peelman F, Staeheli P, Schwemmle M, Devoogdt N, Tersago D, Germani M, Heads J, Henry A, Popplewell A, Ellis M, Brady K, Turner A, Dombrecht B, Stortelers C, Neyts J, Callewaert N, Saelens X. Schepens B, et al. Among authors: sedeyn k. Sci Transl Med. 2021 Nov 24;13(621):eabi7826. doi: 10.1126/scitranslmed.abi7826. Epub 2021 Nov 24. Sci Transl Med. 2021. PMID: 34609205 Free PMC article.
CD8+ T cell immunity against human respiratory syncytial virus.
Rossey I, Sedeyn K, De Baets S, Schepens B, Saelens X. Rossey I, et al. Among authors: sedeyn k. Vaccine. 2014 Oct 21;32(46):6130-7. doi: 10.1016/j.vaccine.2014.08.063. Epub 2014 Sep 16. Vaccine. 2014. PMID: 25223272 Review.
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein.
Schepens B, Sedeyn K, Vande Ginste L, De Baets S, Schotsaert M, Roose K, Houspie L, Van Ranst M, Gilbert B, van Rooijen N, Fiers W, Piedra P, Saelens X. Schepens B, et al. Among authors: sedeyn k. EMBO Mol Med. 2014 Nov;6(11):1436-54. doi: 10.15252/emmm.201404005. EMBO Mol Med. 2014. PMID: 25298406 Free PMC article.
Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.
Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, Sedeyn K, Moschonas GD, Bredow C, Teo QW, Zhang J, Leandro K, Eggermont D, De Sutter D, Boucher K, Hochepied T, Festjens N, Callewaert N, Saelens X, Dermaut B, Knobeloch KP, Beling A, Sanyal S, Radoshevich L, Eyckerman S, Impens F. Thery F, et al. Among authors: sedeyn k. Nat Commun. 2021 Oct 1;12(1):5772. doi: 10.1038/s41467-021-26061-w. Nat Commun. 2021. PMID: 34599178 Free PMC article.
15 results