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Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH 3rd, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, Graham RL, Perry JK, Du Pont V, Pitts J, Ma B, Babusis D, Murakami E, Feng JY, Bilello JP, Porter DP, Cihlar T, Baric RS, Denison MR, Sheahan TP. Pruijssers AJ, et al. Among authors: sheahan tp. Cell Rep. 2020 Jul 21;32(3):107940. doi: 10.1016/j.celrep.2020.107940. Epub 2020 Jul 7. Cell Rep. 2020. PMID: 32668216 Free PMC article.
SARS coronavirus vaccine development.
Baric RS, Sheahan T, Deming D, Donaldson E, Yount B, Sims AC, Roberts RS, Frieman M, Rockx B. Baric RS, et al. Adv Exp Med Biol. 2006;581:553-60. doi: 10.1007/978-0-387-33012-9_101. Adv Exp Med Biol. 2006. PMID: 17037597 Free PMC article. No abstract available.
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
Roberts A, Deming D, Paddock CD, Cheng A, Yount B, Vogel L, Herman BD, Sheahan T, Heise M, Genrich GL, Zaki SR, Baric R, Subbarao K. Roberts A, et al. PLoS Pathog. 2007 Jan;3(1):e5. doi: 10.1371/journal.ppat.0030005. PLoS Pathog. 2007. PMID: 17222058 Free PMC article. Clinical Trial.
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