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Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.
Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, Sher A. Shenderov K, et al. J Immunol. 2013 Jun 1;190(11):5722-30. doi: 10.4049/jimmunol.1203343. Epub 2013 Apr 29. J Immunol. 2013. PMID: 23630357 Free PMC article.
Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.
Mayer-Barber KD, Barber DL, Shenderov K, White SD, Wilson MS, Cheever A, Kugler D, Hieny S, Caspar P, Núñez G, Schlueter D, Flavell RA, Sutterwala FS, Sher A. Mayer-Barber KD, et al. Among authors: shenderov k. J Immunol. 2010 Apr 1;184(7):3326-30. doi: 10.4049/jimmunol.0904189. Epub 2010 Mar 3. J Immunol. 2010. PMID: 20200276 Free PMC article.
Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway.
Shenderov K, Riteau N, Yip R, Mayer-Barber KD, Oland S, Hieny S, Fitzgerald P, Oberst A, Dillon CP, Green DR, Cerundolo V, Sher A. Shenderov K, et al. J Immunol. 2014 Mar 1;192(5):2029-2033. doi: 10.4049/jimmunol.1302549. Epub 2014 Jan 31. J Immunol. 2014. PMID: 24489101 Free PMC article.
Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.
Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, Goldszmid R, McVicar DW, Lyakh L, Trinchieri G. Cardone M, et al. Among authors: shenderov k. PLoS One. 2014 Dec 4;9(12):e114516. doi: 10.1371/journal.pone.0114516. eCollection 2014. PLoS One. 2014. PMID: 25474109 Free PMC article.
Autophagy Controls Acquisition of Aging Features in Macrophages.
Stranks AJ, Hansen AL, Panse I, Mortensen M, Ferguson DJ, Puleston DJ, Shenderov K, Watson AS, Veldhoen M, Phadwal K, Cerundolo V, Simon AK. Stranks AJ, et al. Among authors: shenderov k. J Innate Immun. 2015;7(4):375-91. doi: 10.1159/000370112. Epub 2015 Mar 10. J Innate Immun. 2015. PMID: 25764971 Free PMC article.
15 results