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CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, Chomont N. Fromentin R, et al. Among authors: sinclair e. PLoS Pathog. 2016 Jul 14;12(7):e1005761. doi: 10.1371/journal.ppat.1005761. eCollection 2016 Jul. PLoS Pathog. 2016. PMID: 27415008 Free PMC article.
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.
Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Jain V, et al. Among authors: sinclair e. J Infect Dis. 2013 Oct 15;208(8):1202-11. doi: 10.1093/infdis/jit311. Epub 2013 Jul 12. J Infect Dis. 2013. PMID: 23852127 Free PMC article.
Cortisol patterns are associated with T cell activation in HIV.
Patterson S, Moran P, Epel E, Sinclair E, Kemeny ME, Deeks SG, Bacchetti P, Acree M, Epling L, Kirschbaum C, Hecht FM. Patterson S, et al. Among authors: sinclair e. PLoS One. 2013 Jul 26;8(7):e63429. doi: 10.1371/journal.pone.0063429. Print 2013. PLoS One. 2013. PMID: 23922644 Free PMC article.
Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG. Hatano H, et al. Among authors: sinclair e. PLoS Pathog. 2013;9(10):e1003691. doi: 10.1371/journal.ppat.1003691. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130489 Free PMC article. Clinical Trial.
Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection.
Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW. Lee SA, et al. Among authors: sinclair e. J Infect Dis. 2014 Aug 1;210(3):374-82. doi: 10.1093/infdis/jiu109. Epub 2014 Feb 28. J Infect Dis. 2014. PMID: 24585893 Free PMC article.
CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells.
Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. Cockerham LR, et al. Among authors: sinclair e. PLoS One. 2014 Oct 23;9(10):e110731. doi: 10.1371/journal.pone.0110731. eCollection 2014. PLoS One. 2014. PMID: 25340755 Free PMC article.
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, Chomont N, Fromentin R, Procopio FA, Zeidan J, Palmer S, Odevall L, Johnstone RW, Martin BP, Sinclair E, Deeks SG, Hazuda DJ, Cameron PU, Sékaly RP, Lewin SR. Elliott JH, et al. Among authors: sinclair e. PLoS Pathog. 2014 Nov 13;10(10):e1004473. doi: 10.1371/journal.ppat.1004473. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25393648 Free PMC article. Clinical Trial.
Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy.
Khoury G, Fromentin R, Solomon A, Hartogensis W, Killian M, Hoh R, Somsouk M, Hunt PW, Girling V, Sinclair E, Bacchetti P, Anderson JL, Hecht FM, Deeks SG, Cameron PU, Chomont N, Lewin SR. Khoury G, et al. Among authors: sinclair e. J Infect Dis. 2017 Mar 15;215(6):911-919. doi: 10.1093/infdis/jix039. J Infect Dis. 2017. PMID: 28453847 Free PMC article.
Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants.
Hiener B, Horsburgh BA, Eden JS, Barton K, Schlub TE, Lee E, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. Hiener B, et al. Among authors: sinclair e. Cell Rep. 2017 Oct 17;21(3):813-822. doi: 10.1016/j.celrep.2017.09.081. Cell Rep. 2017. PMID: 29045846 Free PMC article.
Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites.
Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. Lee E, et al. Among authors: sinclair e. J Virol. 2020 Jan 17;94(3):e01270-19. doi: 10.1128/JVI.01270-19. Print 2020 Jan 17. J Virol. 2020. PMID: 31723024 Free PMC article.
322 results