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Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients.
Krijnen PA, Hahn NE, Kholová I, Baylan U, Sipkens JA, van Alphen FP, Vonk AB, Simsek S, Meischl C, Schalkwijk CG, van Buul JD, van Hinsbergh VW, Niessen HW. Krijnen PA, et al. Among authors: sipkens ja. Basic Res Cardiol. 2012 Jan;107(1):233. doi: 10.1007/s00395-011-0233-5. Epub 2011 Dec 14. Basic Res Cardiol. 2012. PMID: 22167343 Free PMC article.
Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase.
Krijnen PA, Sipkens JA, Molling JW, Rauwerda JA, Stehouwer CD, Muller A, Paulus WJ, van Nieuw Amerongen GP, Hack CE, Verhoeven AJ, van Hinsbergh VW, Niessen HW. Krijnen PA, et al. Among authors: sipkens ja. J Mol Cell Cardiol. 2010 Nov;49(5):781-90. doi: 10.1016/j.yjmcc.2010.07.017. Epub 2010 Aug 5. J Mol Cell Cardiol. 2010. PMID: 20691698
Homocysteine-induced apoptosis in endothelial cells coincides with nuclear NOX2 and peri-nuclear NOX4 activity.
Sipkens JA, Hahn N, van den Brand CS, Meischl C, Cillessen SA, Smith DE, Juffermans LJ, Musters RJ, Roos D, Jakobs C, Blom HJ, Smulders YM, Krijnen PA, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW. Sipkens JA, et al. Cell Biochem Biophys. 2013 Nov;67(2):341-52. doi: 10.1007/s12013-011-9297-y. Cell Biochem Biophys. 2013. PMID: 22038300 Free PMC article.
PX-18 Protects Human Saphenous Vein Endothelial Cells under Arterial Blood Pressure.
Kupreishvili K, Stooker W, Emmens RW, Vonk ABA, Sipkens JA, van Dijk A, Eijsman L, Quax PH, van Hinsbergh VWM, Krijnen PAJ, Niessen HWM. Kupreishvili K, et al. Among authors: sipkens ja. Ann Vasc Surg. 2017 Jul;42:293-298. doi: 10.1016/j.avsg.2016.10.063. Epub 2017 Mar 11. Ann Vasc Surg. 2017. PMID: 28300679
Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis.
Sipkens JA, Krijnen PA, Meischl C, Cillessen SA, Smulders YM, Smith DE, Giroth CP, Spreeuwenberg MD, Musters RJ, Muller A, Jakobs C, Roos D, Stehouwer CD, Rauwerda JA, van Hinsbergh VW, Niessen HW. Sipkens JA, et al. Apoptosis. 2007 Aug;12(8):1407-18. doi: 10.1007/s10495-007-0077-5. Apoptosis. 2007. PMID: 17440815 Free PMC article.
Natural killer cells and CD4+ T-cells modulate collateral artery development.
van Weel V, Toes RE, Seghers L, Deckers MM, de Vries MR, Eilers PH, Sipkens J, Schepers A, Eefting D, van Hinsbergh VW, van Bockel JH, Quax PH. van Weel V, et al. Arterioscler Thromb Vasc Biol. 2007 Nov;27(11):2310-8. doi: 10.1161/ATVBAHA.107.151407. Epub 2007 Aug 23. Arterioscler Thromb Vasc Biol. 2007. PMID: 17717295
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