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Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.
Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Cai JP, Zhou J, Yuan S, Kok KH, To KK, Chan IH, Zhang AJ, Sit KY, Au WK, Yuen KY. Chu H, et al. Among authors: sit ky. Clin Infect Dis. 2020 Sep 12;71(6):1400-1409. doi: 10.1093/cid/ciaa410. Clin Infect Dis. 2020. PMID: 32270184 Free PMC article.
Clinical Benefit of Valvular Surgery in Patients with Chronic Kidney Disease.
Chen Y, Au WK, Chan D, Sit KY, Zhen Z, Ho KL, Wong D, Ho LM, Yap D, Lam YM, Lau CP, Tse HF, Chan TM, Yiu KH. Chen Y, et al. Among authors: sit ky. Int Heart J. 2018 Jul 31;59(4):759-765. doi: 10.1536/ihj.17-460. Epub 2018 Jun 20. Int Heart J. 2018. PMID: 29925718 Free article.
Prognostic Value of Tricuspid Valve Geometry and Leaflet Coaptation Status in Patients Undergoing Tricuspid Annuloplasty: A Three-Dimensional Echocardiography Study.
Chen Y, Liu YX, Yu YJ, Wu MZ, Lam YM, Sit KY, Chan DT, Ho CK, Ho LM, Fang LG, Zhang SY, Lau CP, Au WK, Tse HF, Yiu KH. Chen Y, et al. Among authors: sit ky. J Am Soc Echocardiogr. 2019 Dec;32(12):1516-1525. doi: 10.1016/j.echo.2019.07.002. Epub 2019 Sep 25. J Am Soc Echocardiogr. 2019. PMID: 31563435
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.
Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. Riva L, et al. Among authors: sit ky. Nature. 2020 Oct;586(7827):113-119. doi: 10.1038/s41586-020-2577-1. Epub 2020 Jul 24. Nature. 2020. PMID: 32707573 Free PMC article.
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung.
Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Chan IH, Sit KY, Foo DC, Wong IY, Ng AT, Cheung TT, Law SY, Au WK, Brindley MA, Chen Z, Kok KH, Chan JF, Yuen KY. Chu H, et al. Among authors: sit ky. Nat Commun. 2021 Jan 8;12(1):134. doi: 10.1038/s41467-020-20457-w. Nat Commun. 2021. PMID: 33420022 Free PMC article.
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2.
Yuan S, Yin X, Meng X, Chan JF, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan CC, Poon VK, Lee AC, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Lau CY, Sit KY, Au WK, Wang R, Zhang YY, Tang YD, Clausen TM, Pihl J, Oh J, Sze KH, Zhang AJ, Chu H, Kok KH, Wang D, Cai XH, Esko JD, Hung IF, Li RA, Chen H, Sun H, Jin DY, Sun R, Chanda SK, Yuen KY. Yuan S, et al. Among authors: sit ky. Nature. 2021 May;593(7859):418-423. doi: 10.1038/s41586-021-03431-4. Epub 2021 Mar 16. Nature. 2021. PMID: 33727703
SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo.
Hui KPY, Ho JCW, Cheung MC, Ng KC, Ching RHH, Lai KL, Kam TT, Gu H, Sit KY, Hsin MKY, Au TWK, Poon LLM, Peiris M, Nicholls JM, Chan MCW. Hui KPY, et al. Among authors: sit ky. Nature. 2022 Mar;603(7902):715-720. doi: 10.1038/s41586-022-04479-6. Epub 2022 Feb 1. Nature. 2022. PMID: 35104836
Prevalence and Prognostic Importance of Massive Tricuspid Regurgitation in Patients Undergoing Tricuspid Annuloplasty With Concomitant Left-Sided Valve Surgery: A Study on Rheumatic Valvular Heart Disease.
Chen Y, Chan YH, Wu MZ, Yu YJ, Lam YM, Sit KY, Chan DT, Ho CK, Ho LM, Lau CP, Au WK, Tse HF, Yiu KH. Chen Y, et al. Among authors: sit ky. Front Cardiovasc Med. 2022 Jan 27;9:686208. doi: 10.3389/fcvm.2022.686208. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35155624 Free PMC article.
28 results