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High expression of the urokinase plasminogen activator and its cognate receptor associates with advanced stages and reduced disease-free interval in papillary thyroid carcinoma.
Ulisse S, Baldini E, Sorrenti S, Barollo S, Gnessi L, Catania A, Pellizzo MR, Nardi F, Mian C, De Antoni E, D'Armiento M, Frati L. Ulisse S, et al. Among authors: sorrenti s. J Clin Endocrinol Metab. 2011 Feb;96(2):504-8. doi: 10.1210/jc.2010-1688. Epub 2010 Nov 24. J Clin Endocrinol Metab. 2011. PMID: 21106716
Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT.
Baldini E, Arlot-Bonnemains Y, Sorrenti S, Mian C, Pelizzo MR, De Antoni E, Palermo S, Morrone S, Barollo S, Nesca A, Moretti CG, D'Armiento M, Ulisse S. Baldini E, et al. Among authors: sorrenti s. BMC Cancer. 2011 Sep 26;11:411. doi: 10.1186/1471-2407-11-411. BMC Cancer. 2011. PMID: 21943074 Free PMC article.
In papillary thyroid carcinoma BRAFV600E is associated with increased expression of the urokinase plasminogen activator and its cognate receptor, but not with disease-free interval.
Ulisse S, Baldini E, Sorrenti S, Barollo S, Prinzi N, Catania A, Nesca A, Gnessi L, Pelizzo MR, Mian C, De Vito C, Calvanese A, Palermo S, Persechino S, De Antoni E, D'Armiento M. Ulisse S, et al. Among authors: sorrenti s. Clin Endocrinol (Oxf). 2012 Nov;77(5):780-6. doi: 10.1111/j.1365-2265.2012.04465.x. Clin Endocrinol (Oxf). 2012. PMID: 22702340
160 results