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Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling.
Cell Rep. 2020 Mar 10;30(10):3383-3396.e7. doi: 10.1016/j.celrep.2020.02.014.
Cell Rep. 2020.
PMID: 32160544
Free PMC article.
Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process.
Day EK, Sosale NG, Lazzara MJ.
Day EK, et al. Among authors: sosale ng.
Curr Opin Biotechnol. 2016 Aug;40:185-192. doi: 10.1016/j.copbio.2016.06.005. Epub 2016 Jul 6.
Curr Opin Biotechnol. 2016.
PMID: 27393828
Free PMC article.
Review.
Item in Clipboard
CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer.
Cornelison R, Biswas K, Llaneza DC, Harris AR, Sosale NG, Lazzara MJ, Landen CN.
Cornelison R, et al. Among authors: sosale ng.
Cancers (Basel). 2021 Oct 9;13(20):5056. doi: 10.3390/cancers13205056.
Cancers (Basel). 2021.
PMID: 34680204
Free PMC article.
Item in Clipboard
Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex.
D'Souza RS, Lim JY, Turgut A, Servage K, Zhang J, Orth K, Sosale NG, Lazzara MJ, Allegood J, Casanova JE.
D'Souza RS, et al. Among authors: sosale ng.
Elife. 2020 Apr 1;9:e54113. doi: 10.7554/eLife.54113.
Elife. 2020.
PMID: 32234213
Free PMC article.
Item in Clipboard
Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties.
Sosale NG, Spinler KR, Alvey C, Discher DE.
Sosale NG, et al.
Curr Opin Immunol. 2015 Aug;35:107-12. doi: 10.1016/j.coi.2015.06.013. Epub 2015 Jul 13.
Curr Opin Immunol. 2015.
PMID: 26172292
Free PMC article.
Review.
Item in Clipboard
Cell rigidity and shape override CD47's "self"-signaling in phagocytosis by hyperactivating myosin-II.
Sosale NG, Rouhiparkouhi T, Bradshaw AM, Dimova R, Lipowsky R, Discher DE.
Sosale NG, et al.
Blood. 2015 Jan 15;125(3):542-52. doi: 10.1182/blood-2014-06-585299. Epub 2014 Nov 19.
Blood. 2015.
PMID: 25411427
Free PMC article.
Item in Clipboard
Marker-of-self becomes marker-of-senescence.
Sosale N, Discher DE.
Sosale N, et al.
Blood. 2012 Jun 7;119(23):5343-4. doi: 10.1182/blood-2012-04-418608.
Blood. 2012.
PMID: 22679336
Free article.
No abstract available.
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"Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors.
Sosale NG, Ivanovska II, Tsai RK, Swift J, Hsu JW, Alvey CM, Zoltick PW, Discher DE.
Sosale NG, et al.
Mol Ther Methods Clin Dev. 2016 Dec 7;3:16080. doi: 10.1038/mtm.2016.80. eCollection 2016.
Mol Ther Methods Clin Dev. 2016.
PMID: 28053997
Free PMC article.
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