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Elucidation of the RamA regulon in Klebsiella pneumoniae reveals a role in LPS regulation.
De Majumdar S, Yu J, Fookes M, McAteer SP, Llobet E, Finn S, Spence S, Monahan A, Monaghan A, Kissenpfennig A, Ingram RJ, Bengoechea J, Gally DL, Fanning S, Elborn JS, Schneiders T. De Majumdar S, et al. Among authors: spence s. PLoS Pathog. 2015 Jan 29;11(1):e1004627. doi: 10.1371/journal.ppat.1004627. eCollection 2015 Jan. PLoS Pathog. 2015. PMID: 25633080 Free PMC article.
Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.
Knosp CA, Schiering C, Spence S, Carroll HP, Nel HJ, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald DC, Powrie F, Fallon PG, Johnston JA, Kissenpfennig A. Knosp CA, et al. Among authors: spence s. J Immunol. 2013 Apr 1;190(7):3235-45. doi: 10.4049/jimmunol.1201396. Epub 2013 Mar 1. J Immunol. 2013. PMID: 23455506 Free PMC article.
Btk regulates macrophage polarization in response to lipopolysaccharide.
Ní Gabhann J, Hams E, Smith S, Wynne C, Byrne JC, Brennan K, Spence S, Kissenpfennig A, Johnston JA, Fallon PG, Jefferies CA. Ní Gabhann J, et al. Among authors: spence s. PLoS One. 2014 Jan 21;9(1):e85834. doi: 10.1371/journal.pone.0085834. eCollection 2014. PLoS One. 2014. PMID: 24465735 Free PMC article.
SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses.
Knosp CA, Carroll HP, Elliott J, Saunders SP, Nel HJ, Amu S, Pratt JC, Spence S, Doran E, Cooke N, Jackson R, Swift J, Fitzgerald DC, Heaney LG, Fallon PG, Kissenpfennig A, Johnston JA. Knosp CA, et al. Among authors: spence s. J Exp Med. 2011 Jul 4;208(7):1523-31. doi: 10.1084/jem.20101167. Epub 2011 Jun 6. J Exp Med. 2011. PMID: 21646394 Free PMC article.
Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Spence S, Greene MK, Fay F, Hams E, Saunders SP, Hamid U, Fitzgerald M, Beck J, Bains BK, Smyth P, Themistou E, Small DM, Schmid D, O'Kane CM, Fitzgerald DC, Abdelghany SM, Johnston JA, Fallon PG, Burrows JF, McAuley DF, Kissenpfennig A, Scott CJ. Spence S, et al. Sci Transl Med. 2015 Sep 2;7(303):303ra140. doi: 10.1126/scitranslmed.aab3459. Sci Transl Med. 2015. PMID: 26333936
Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity.
Schmid D, Jarvis GE, Fay F, Small DM, Greene MK, Majkut J, Spence S, McLaughlin KM, McCloskey KD, Johnston PG, Kissenpfennig A, Longley DB, Scott CJ. Schmid D, et al. Among authors: spence s. Cell Death Dis. 2014 Oct 9;5(10):e1454. doi: 10.1038/cddis.2014.413. Cell Death Dis. 2014. PMID: 25299779 Free PMC article.
Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.
Spence S, Fitzsimons A, Boyd CR, Kessler J, Fitzgerald D, Elliott J, Gabhann JN, Smith S, Sica A, Hams E, Saunders SP, Jefferies CA, Fallon PG, McAuley DF, Kissenpfennig A, Johnston JA. Spence S, et al. Immunity. 2013 Jan 24;38(1):66-78. doi: 10.1016/j.immuni.2012.09.013. Epub 2012 Nov 21. Immunity. 2013. PMID: 23177319 Free article. Retracted.
576 results