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Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells.
Marinkovic G, Hibender S, Hoogenboezem M, van Broekhoven A, Girigorie AF, Bleeker N, Hamers AA, Stap J, van Buul JD, de Vries CJ, de Waard V. Marinkovic G, et al. Among authors: stap j. Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2380-8. doi: 10.1161/ATVBAHA.113.301394. Epub 2013 Aug 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23950142
Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2.
Wiemhoefer A, Stargardt A, van der Linden WA, Renner MC, van Kesteren RE, Stap J, Raspe MA, Tomkinson B, Kessels HW, Ovaa H, Overkleeft HS, Florea B, Reits EA. Wiemhoefer A, et al. Among authors: stap j. Mol Cell Proteomics. 2015 Aug;14(8):2177-93. doi: 10.1074/mcp.M114.043331. Epub 2015 Jun 3. Mol Cell Proteomics. 2015. PMID: 26041847 Free PMC article.
Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.
Krawczyk PM, Eppink B, Essers J, Stap J, Rodermond H, Odijk H, Zelensky A, van Bree C, Stalpers LJ, Buist MR, Soullié T, Rens J, Verhagen HJ, O'Connor MJ, Franken NA, Ten Hagen TL, Kanaar R, Aten JA. Krawczyk PM, et al. Among authors: stap j. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9851-6. doi: 10.1073/pnas.1101053108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555554 Free PMC article.
Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles.
Böing AN, Stap J, Hau CM, Afink GB, Ris-Stalpers C, Reits EA, Sturk A, van Noorden CJ, Nieuwland R. Böing AN, et al. Among authors: stap j. Biochim Biophys Acta. 2013 Aug;1833(8):1844-52. doi: 10.1016/j.bbamcr.2013.03.013. Epub 2013 Mar 24. Biochim Biophys Acta. 2013. PMID: 23531593 Free article.
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
Molenaar RJ, Botman D, Smits MA, Hira VV, van Lith SA, Stap J, Henneman P, Khurshed M, Lenting K, Mul AN, Dimitrakopoulou D, van Drunen CM, Hoebe RA, Radivoyevitch T, Wilmink JW, Maciejewski JP, Vandertop WP, Leenders WP, Bleeker FE, van Noorden CJ. Molenaar RJ, et al. Among authors: stap j. Cancer Res. 2015 Nov 15;75(22):4790-802. doi: 10.1158/0008-5472.CAN-14-3603. Epub 2015 Sep 11. Cancer Res. 2015. PMID: 26363012
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