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Abeta-globulomers are formed independently of the fibril pathway.
Gellermann GP, Byrnes H, Striebinger A, Ullrich K, Mueller R, Hillen H, Barghorn S. Gellermann GP, et al. Among authors: striebinger a. Neurobiol Dis. 2008 May;30(2):212-20. doi: 10.1016/j.nbd.2008.01.010. Epub 2008 Feb 15. Neurobiol Dis. 2008. PMID: 18353662
Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies.
Hillen H, Barghorn S, Striebinger A, Labkovsky B, Müller R, Nimmrich V, Nolte MW, Perez-Cruz C, van der Auwera I, van Leuven F, van Gaalen M, Bespalov AY, Schoemaker H, Sullivan JP, Ebert U. Hillen H, et al. Among authors: striebinger a. J Neurosci. 2010 Aug 4;30(31):10369-79. doi: 10.1523/JNEUROSCI.5721-09.2010. J Neurosci. 2010. PMID: 20685980 Free PMC article.
Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer's disease brain.
Frey B, Holzinger D, Taylor K, Ehrnhoefer DE, Striebinger A, Biesinger S, Gasparini L, O'Neill MJ, Wegner F, Barghorn S, Höglinger GU, Heym RG. Frey B, et al. Among authors: striebinger a. Acta Neuropathol Commun. 2023 Nov 14;11(1):181. doi: 10.1186/s40478-023-01676-w. Acta Neuropathol Commun. 2023. PMID: 37964332 Free PMC article.
Tau in the brain interstitial fluid is fragmented and seeding-competent.
Barini E, Plotzky G, Mordashova Y, Hoppe J, Rodriguez-Correa E, Julier S, LePrieult F, Mairhofer I, Mezler M, Biesinger S, Cik M, Meinhardt MW, Ercan-Herbst E, Ehrnhoefer DE, Striebinger A, Bodie K, Klein C, Gasparini L, Schlegel K. Barini E, et al. Among authors: striebinger a. Neurobiol Aging. 2022 Jan;109:64-77. doi: 10.1016/j.neurobiolaging.2021.09.013. Epub 2021 Sep 17. Neurobiol Aging. 2022. PMID: 34655982 Free article.