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Adaptive designs in clinical trials: why use them, and how to run and report them.
Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T. Pallmann P, et al. Among authors: sydes mr. BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7. BMC Med. 2018. PMID: 29490655 Free PMC article.
Outcomes and endpoints in cancer trials: bridging the divide.
Wilson MK, Collyar D, Chingos DT, Friedlander M, Ho TW, Karakasis K, Kaye S, Parmar MK, Sydes MR, Tannock IF, Oza AM. Wilson MK, et al. Among authors: sydes mr. Lancet Oncol. 2015 Jan;16(1):e43-52. doi: 10.1016/S1470-2045(14)70380-8. Epub 2014 Dec 29. Lancet Oncol. 2015. PMID: 25638556 Review.
Best practice for analysis of shared clinical trial data.
Hollis S, Fletcher C, Lynn F, Urban HJ, Branson J, Burger HU, Tudur Smith C, Sydes MR, Gerlinger C. Hollis S, et al. Among authors: sydes mr. BMC Med Res Methodol. 2016 Jul 8;16 Suppl 1(Suppl 1):76. doi: 10.1186/s12874-016-0170-y. BMC Med Res Methodol. 2016. PMID: 27410240 Free PMC article.
Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols.
Parmar MK, Sydes MR, Cafferty FH, Choodari-Oskooei B, Langley RE, Brown L, Phillips PP, Spears MR, Rowley S, Kaplan R, James ND, Maughan T, Paton N, Royston PJ. Parmar MK, et al. Among authors: sydes mr. Clin Trials. 2017 Oct;14(5):451-461. doi: 10.1177/1740774517725697. Epub 2017 Aug 22. Clin Trials. 2017. PMID: 28830236 Free PMC article.
253 results