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Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team.
Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, Yates JC, Tal-Singer R; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints Study Investigators. Vestbo J, et al. Am J Respir Crit Care Med. 2014 May 1;189(9):1022-30. doi: 10.1164/rccm.201311-2006PP. Am J Respir Crit Care Med. 2014. PMID: 24552242 Clinical Trial.
Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort.
Lomas DA, Silverman EK, Edwards LD, Miller BE, Coxson HO, Tal-Singer R; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. Lomas DA, et al. Thorax. 2008 Dec;63(12):1058-63. doi: 10.1136/thx.2008.102574. Epub 2008 Aug 29. Thorax. 2008. PMID: 18757456
Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD.
Lomas DA, Silverman EK, Edwards LD, Locantore NW, Miller BE, Horstman DH, Tal-Singer R; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators. Lomas DA, et al. Eur Respir J. 2009 Jul;34(1):95-102. doi: 10.1183/09031936.00156508. Epub 2009 Jan 22. Eur Respir J. 2009. PMID: 19164344 Free article.
Variants in FAM13A are associated with chronic obstructive pulmonary disease.
Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK. Cho MH, et al. Nat Genet. 2010 Mar;42(3):200-2. doi: 10.1038/ng.535. Epub 2010 Feb 21. Nat Genet. 2010. PMID: 20173748 Free PMC article.
Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort.
Spruit MA, Watkins ML, Edwards LD, Vestbo J, Calverley PM, Pinto-Plata V, Celli BR, Tal-Singer R, Wouters EF; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study investigators. Spruit MA, et al. Respir Med. 2010 Jun;104(6):849-57. doi: 10.1016/j.rmed.2009.12.007. Epub 2010 May 14. Respir Med. 2010. PMID: 20471236 Free article.
Characterisation of COPD heterogeneity in the ECLIPSE cohort.
Agusti A, Calverley PM, Celli B, Coxson HO, Edwards LD, Lomas DA, MacNee W, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Wouters E, Yates JC, Vestbo J; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. Agusti A, et al. Respir Res. 2010 Sep 10;11(1):122. doi: 10.1186/1465-9921-11-122. Respir Res. 2010. PMID: 20831787 Free PMC article. Clinical Trial.
239 results