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Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis.
Lenoir O, Milon M, Virsolvy A, Hénique C, Schmitt A, Massé JM, Kotelevtsev Y, Yanagisawa M, Webb DJ, Richard S, Tharaux PL. Lenoir O, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2014 May;25(5):1050-62. doi: 10.1681/ASN.2013020195. Epub 2014 Apr 10. J Am Soc Nephrol. 2014. PMID: 24722437 Free PMC article.
Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN.
Henique C, Bollee G, Lenoir O, Dhaun N, Camus M, Chipont A, Flosseau K, Mandet C, Yamamoto M, Karras A, Thervet E, Bruneval P, Nochy D, Mesnard L, Tharaux PL. Henique C, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2016 Jan;27(1):172-88. doi: 10.1681/ASN.2014111080. Epub 2015 May 21. J Am Soc Nephrol. 2016. PMID: 25999406 Free PMC article.
A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney.
Mami I, Tavernier Q, Bouvier N, Aboukamis R, Desbuissons G, Rabant M, Poindessous V, Laurent-Puig P, Beaune P, Tharaux PL, Thervet E, Chevet E, Anglicheau D, Pallet N. Mami I, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2016 Sep;27(9):2670-83. doi: 10.1681/ASN.2015060703. Epub 2016 Jan 28. J Am Soc Nephrol. 2016. PMID: 26823555 Free PMC article.
Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage.
Suarez-Alvarez B, Morgado-Pascual JL, Rayego-Mateos S, Rodriguez RM, Rodrigues-Diez R, Cannata-Ortiz P, Sanz AB, Egido J, Tharaux PL, Ortiz A, Lopez-Larrea C, Ruiz-Ortega M. Suarez-Alvarez B, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2017 Feb;28(2):504-519. doi: 10.1681/ASN.2015080910. Epub 2016 Jul 19. J Am Soc Nephrol. 2017. PMID: 27436852 Free PMC article.
Sildenafil Prevents Podocyte Injury via PPAR-γ-Mediated TRPC6 Inhibition.
Sonneveld R, Hoenderop JG, Isidori AM, Henique C, Dijkman HB, Berden JH, Tharaux PL, van der Vlag J, Nijenhuis T. Sonneveld R, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2017 May;28(5):1491-1505. doi: 10.1681/ASN.2015080885. Epub 2016 Nov 28. J Am Soc Nephrol. 2017. PMID: 27895156 Free PMC article.
Targeting mTOR Signaling Can Prevent the Progression of FSGS.
Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, Huber TB. Zschiedrich S, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2017 Jul;28(7):2144-2157. doi: 10.1681/ASN.2016050519. Epub 2017 Mar 7. J Am Soc Nephrol. 2017. PMID: 28270414 Free PMC article.
Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension.
Luque Y, Lenoir O, Bonnin P, Hardy L, Chipont A, Placier S, Vandermeersch S, Xu-Dubois YC, Robin B, Lazareth H, Souyri M, Guyonnet L, Baudrie V, Camerer E, Rondeau E, Mesnard L, Tharaux PL. Luque Y, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2017 Dec;28(12):3563-3578. doi: 10.1681/ASN.2016090960. Epub 2017 Sep 19. J Am Soc Nephrol. 2017. PMID: 28928136 Free PMC article.
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis.
Henique C, Bollée G, Loyer X, Grahammer F, Dhaun N, Camus M, Vernerey J, Guyonnet L, Gaillard F, Lazareth H, Meyer C, Bensaada I, Legrès L, Satoh T, Akira S, Bruneval P, Dimmeler S, Tedgui A, Karras A, Thervet E, Nochy D, Huber TB, Mesnard L, Lenoir O, Tharaux PL. Henique C, et al. Among authors: tharaux pl. Nat Commun. 2017 Nov 28;8(1):1829. doi: 10.1038/s41467-017-01885-7. Nat Commun. 2017. PMID: 29184126 Free PMC article.
162 results