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Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.
Thi Nhu Thao T, Labroussaa F, Ebert N, V'kovski P, Stalder H, Portmann J, Kelly J, Steiner S, Holwerda M, Kratzel A, Gultom M, Schmied K, Laloli L, Hüsser L, Wider M, Pfaender S, Hirt D, Cippà V, Crespo-Pomar S, Schröder S, Muth D, Niemeyer D, Corman VM, Müller MA, Drosten C, Dijkman R, Jores J, Thiel V. Thi Nhu Thao T, et al. Among authors: thiel v, v kovski p. Nature. 2020 Jun;582(7813):561-565. doi: 10.1038/s41586-020-2294-9. Epub 2020 May 4. Nature. 2020. PMID: 32365353
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.
Pfefferle S, Schöpf J, Kögl M, Friedel CC, Müller MA, Carbajo-Lozoya J, Stellberger T, von Dall'Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Züst R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel HJ, Schwegmann-Wessels C, Pöhlmann S, Haas J, Drosten C, von Brunn A. Pfefferle S, et al. Among authors: thiel v, thiel hj. PLoS Pathog. 2011 Oct;7(10):e1002331. doi: 10.1371/journal.ppat.1002331. Epub 2011 Oct 27. PLoS Pathog. 2011. PMID: 22046132 Free PMC article.
Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination.
van den Worm SH, Eriksson KK, Zevenhoven JC, Weber F, Züst R, Kuri T, Dijkman R, Chang G, Siddell SG, Snijder EJ, Thiel V, Davidson AD. van den Worm SH, et al. Among authors: thiel v. PLoS One. 2012;7(3):e32857. doi: 10.1371/journal.pone.0032857. Epub 2012 Mar 7. PLoS One. 2012. PMID: 22412934 Free PMC article.
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.
Raj VS, Mou H, Smits SL, Dekkers DH, Müller MA, Dijkman R, Muth D, Demmers JA, Zaki A, Fouchier RA, Thiel V, Drosten C, Rottier PJ, Osterhaus AD, Bosch BJ, Haagmans BL. Raj VS, et al. Among authors: thiel v. Nature. 2013 Mar 14;495(7440):251-4. doi: 10.1038/nature12005. Nature. 2013. PMID: 23486063 Free PMC article.
TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
Bertram S, Dijkman R, Habjan M, Heurich A, Gierer S, Glowacka I, Welsch K, Winkler M, Schneider H, Hofmann-Winkler H, Thiel V, Pöhlmann S. Bertram S, et al. Among authors: thiel v. J Virol. 2013 Jun;87(11):6150-60. doi: 10.1128/JVI.03372-12. Epub 2013 Mar 27. J Virol. 2013. PMID: 23536651 Free PMC article.
Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.
Lundin A, Dijkman R, Bergström T, Kann N, Adamiak B, Hannoun C, Kindler E, Jónsdóttir HR, Muth D, Kint J, Forlenza M, Müller MA, Drosten C, Thiel V, Trybala E. Lundin A, et al. Among authors: thiel v. PLoS Pathog. 2014 May 29;10(5):e1004166. doi: 10.1371/journal.ppat.1004166. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24874215 Free PMC article.
314 results