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Phase I dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer.
Herbst RS, Eckhardt SG, Kurzrock R, Ebbinghaus S, O'Dwyer PJ, Gordon MS, Novotny W, Goldwasser MA, Tohnya TM, Lum BL, Ashkenazi A, Jubb AM, Mendelson DS. Herbst RS, et al. Among authors: tohnya tm. J Clin Oncol. 2010 Jun 10;28(17):2839-46. doi: 10.1200/JCO.2009.25.1991. Epub 2010 May 10. J Clin Oncol. 2010. PMID: 20458040 Clinical Trial.
A phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignancies.
Camidge DR, Herbst RS, Gordon MS, Eckhardt SG, Kurzrock R, Durbin B, Ing J, Tohnya TM, Sager J, Ashkenazi A, Bray G, Mendelson D. Camidge DR, et al. Among authors: tohnya tm. Clin Cancer Res. 2010 Feb 15;16(4):1256-63. doi: 10.1158/1078-0432.CCR-09-1267. Epub 2010 Feb 9. Clin Cancer Res. 2010. PMID: 20145186 Clinical Trial.
Immunomodulation of multiple myeloma.
Tohnya TM, Figg WD. Tohnya TM, et al. Cancer Biol Ther. 2004 Nov;3(11):1060-1. doi: 10.4161/cbt.3.11.1303. Epub 2004 Nov 12. Cancer Biol Ther. 2004. PMID: 15640623 Review.
Phase I trial of 7-hydroxystaurosporine and fludararbine phosphate: in vivo evidence of 7-hydroxystaurosporine induced apoptosis in chronic lymphocytic leukemia.
Marti GE, Stetler-Stevenson M, Grant ND, White T, Figg WD, Tohnya T, Jaffe ES, Dunleavy K, Janik JE, Steinberg SM, Wilson WH. Marti GE, et al. Leuk Lymphoma. 2011 Dec;52(12):2284-92. doi: 10.3109/10428194.2011.589547. Epub 2011 Jul 12. Leuk Lymphoma. 2011. PMID: 21745173 Free PMC article. Clinical Trial.
Cyclooxygenase-2 and angiogenesis in prostate cancer.
Tkacz VL, Tohnya TM, Figg WD. Tkacz VL, et al. Among authors: tohnya tm. Cancer Biol Ther. 2005 Aug;4(8):813-4. doi: 10.4161/cbt.4.8.2089. Cancer Biol Ther. 2005. PMID: 16123581