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Rapid decline of neutralizing antibodies is associated with decay of IgM in adults recovered from mild COVID-19.
Harrington WE, Trakhimets O, Andrade DV, Dambrauskas N, Raappana A, Jiang Y, Houck J, Selman W, Yang A, Vigdorovich V, Yeung W, Haglund M, Wallner J, Oldroyd A, Hardy S, Stewart SWA, Gervassi A, Van Voorhis W, Frenkel L, Sather DN. Harrington WE, et al. Among authors: trakhimets o. Cell Rep Med. 2021 Apr 20;2(4):100253. doi: 10.1016/j.xcrm.2021.100253. Epub 2021 Apr 5. Cell Rep Med. 2021. PMID: 33842901 Free PMC article.
Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage.
Vijayan K, Visweswaran GRR, Chandrasekaran R, Trakhimets O, Brown SL, Watson A, Zuck M, Dambrauskas N, Raappana A, Carbonetti S, Kelnhofer-Millevolte L, Glennon EKK, Postiglione R, Sather DN, Kaushansky A. Vijayan K, et al. Among authors: trakhimets o. Cell Rep. 2021 Aug 3;36(5):109489. doi: 10.1016/j.celrep.2021.109489. Cell Rep. 2021. PMID: 34348141 Free article.
Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies.
Wilder BK, Vigdorovich V, Carbonetti S, Minkah N, Hertoghs N, Raappana A, Cardamone H, Oliver BG, Trakhimets O, Kumar S, Dambrauskas N, Arredondo SA, Camargo N, Seilie AM, Murphy SC, Kappe SHI, Sather DN. Wilder BK, et al. Among authors: trakhimets o. NPJ Vaccines. 2022 May 26;7(1):58. doi: 10.1038/s41541-022-00480-2. NPJ Vaccines. 2022. PMID: 35618791 Free PMC article.
Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection.
Visweswaran GRR, Vijayan K, Chandrasekaran R, Trakhimets O, Brown SL, Vigdorovich V, Yang A, Raappana A, Watson A, Selman W, Zuck M, Dambrauskas N, Kaushansky A, Sather DN. Visweswaran GRR, et al. Among authors: trakhimets o. PLoS Pathog. 2022 Jul 6;18(7):e1010671. doi: 10.1371/journal.ppat.1010671. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35793394 Free PMC article.
A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection.
Schäfer C, Roobsoong W, Kangwanrangsan N, Bardelli M, Rawlinson TA, Dambrauskas N, Trakhimets O, Parthiban C, Goswami D, Reynolds LM, Kennedy SY, Flannery EL, Murphy SC, Sather DN, Draper SJ, Sattabongkot J, Mikolajczak SA, Kappe SHI. Schäfer C, et al. Among authors: trakhimets o. iScience. 2020 Aug 21;23(8):101381. doi: 10.1016/j.isci.2020.101381. Epub 2020 Jul 18. iScience. 2020. PMID: 32739836 Free PMC article.