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SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback.
Coelho CH, Bloom N, Ramirez SI, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S; Accelerating COVID-19 Therapeutic Interventions and Vaccines–2/A5401 (ACTIV-2/A5401) Study Team. Coelho CH, et al. bioRxiv [Preprint]. 2023 Nov 22:2023.11.21.567575. doi: 10.1101/2023.11.21.567575. bioRxiv. 2023. PMID: 38045374 Free PMC article. Preprint.
A systems vaccinology resource to develop and test computational models of immunity.
Shinde P, Soldevila F, Reyna J, Aoki M, Rasmussen M, Willemsen L, Kojima M, Ha B, Greenbaum JA, Overton JA, Guzman-Orozco H, Nili S, Orfield S, Gygi JP, da Silva Antunes R, Sette A, Grant B, Olsen LR, Konstorum A, Guan L, Ay F, Kleinstein SH, Peters B. Shinde P, et al. bioRxiv [Preprint]. 2023 Aug 29:2023.08.28.555193. doi: 10.1101/2023.08.28.555193. bioRxiv. 2023. PMID: 37693565 Free PMC article. Updated. Preprint.
T cell reactivity to Bordetella pertussis is highly diverse regardless of childhood vaccination.
da Silva Antunes R, Garrigan E, Quiambao LG, Dhanda SK, Marrama D, Westernberg L, Wang E, Abawi A, Sutherland A, Armstrong SK, Brickman TJ, Sidney J, Frazier A, Merkel TJ, Peters B, Sette A. da Silva Antunes R, et al. Cell Host Microbe. 2023 Aug 9;31(8):1404-1416.e4. doi: 10.1016/j.chom.2023.06.015. Epub 2023 Jul 24. Cell Host Microbe. 2023. PMID: 37490913
Dynamic activity in cis-regulatory elements of leukocytes identifies transcription factor activation and stratifies COVID-19 severity in ICU patients.
Lam MTY, Duttke SH, Odish MF, Le HD, Hansen EA, Nguyen CT, Trescott S, Kim R, Deota S, Chang MW, Patel A, Hepokoski M, Alotaibi M, Rolfsen M, Perofsky K, Warden AS, Foley J, Ramirez SI, Dan JM, Abbott RK, Crotty S, Crotty Alexander LE, Malhotra A, Panda S, Benner CW, Coufal NG. Lam MTY, et al. Cell Rep Med. 2023 Feb 21;4(2):100935. doi: 10.1016/j.xcrm.2023.100935. Epub 2023 Jan 25. Cell Rep Med. 2023. PMID: 36758547 Free PMC article.
Very Low Driving-Pressure Ventilation in Patients With COVID-19 Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation: A Physiologic Study.
Odish M, Pollema T, Meier A, Hepokoski M, Yi C, Spragg R, Patel HH, Alexander LEC, Sun XS, Jain S, Simonson TS, Malhotra A, Owens RL. Odish M, et al. J Cardiothorac Vasc Anesth. 2023 Mar;37(3):423-431. doi: 10.1053/j.jvca.2022.11.033. Epub 2022 Nov 28. J Cardiothorac Vasc Anesth. 2023. PMID: 36567221 Free PMC article.
Acute and Post-Acute COVID-19 Outcomes Among Immunologically Naïve Adults During Delta Versus Omicron Waves.
Doll MK, Waghmare A, Heit A, Levenson Shakoor B, Kimball LE, Ozbek N, Blazevic RL, Mose L, Boonyaratanakornkit J, Stevens-Ayers TL, Cornell K, Sheppard BD, Hampson E, Sharmin F, Goodwin B, Dan JM, Archie T, O'Connor T, Heckerman D, Schmitz F, Boeckh M, Crotty S. Doll MK, et al. medRxiv [Preprint]. 2022 Nov 14:2022.11.13.22282222. doi: 10.1101/2022.11.13.22282222. medRxiv. 2022. PMID: 36425923 Free PMC article. Updated. Preprint.
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.
Bowen JE, Park YJ, Stewart C, Brown JT, Sharkey WK, Walls AC, Joshi A, Sprouse KR, McCallum M, Tortorici MA, Franko NM, Logue JK, Mazzitelli IG, Nguyen AW, Silva RP, Huang Y, Low JS, Jerak J, Tiles SW, Ahmed K, Shariq A, Dan JM, Zhang Z, Weiskopf D, Sette A, Snell G, Posavad CM, Iqbal NT, Geffner J, Bandera A, Gori A, Sallusto F, Maynard JA, Crotty S, Van Voorhis WC, Simmerling C, Grifantini R, Chu HY, Corti D, Veesler D. Bowen JE, et al. Sci Immunol. 2022 Dec 23;7(78):eadf1421. doi: 10.1126/sciimmunol.adf1421. Epub 2022 Dec 23. Sci Immunol. 2022. PMID: 36356052 Free PMC article.
53 results