U19 AI142784/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Subject: U19 AI142784/AI/NIAID NIH HHS/United States[Grant - PubMed

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Results by year

Year	Number of Results
2019	5
2020	13
2021	16
2022	9
2023	14
2024	2

53 results

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Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in mice.

Feng S, McNehlan ME, Kinsella RL, Sur Chowdhury C, Chavez SM, Naik SK, McKee SR, Van Winkle JA, Dubey N, Samuels A, Swain A, Cui X, Hendrix SV, Woodson R, Kreamalmeyer D, Smirnov A, Artyomov MN, Virgin HW, Wang YT, Stallings CL. Feng S, et al. Nat Microbiol. 2024 Mar;9(3):684-697. doi: 10.1038/s41564-024-01608-x. Epub 2024 Feb 27. Nat Microbiol. 2024. PMID: 38413834

CDKL5 regulates p62-mediated selective autophagy and confers protection against neurotropic viruses.

Thinwa JW, Zou Z, Parks E, Sebti S, Hui K, Wei Y, Goodarzi M, Singh V, Urquhart G, Jewell JL, Pfeiffer JK, Levine B, Reese TA, Shiloh MU. Thinwa JW, et al. J Clin Invest. 2024 Jan 2;134(1):e168544. doi: 10.1172/JCI168544. J Clin Invest. 2024. PMID: 37917202 Free PMC article.

Autophagy gene-dependent intracellular immunity triggered by interferon-γ.

McAllaster MR, Bhushan J, Balce DR, Orvedahl A, Park A, Hwang S, Sullender ME, Sibley LD, Virgin HW. McAllaster MR, et al. mBio. 2023 Oct 31;14(6):e0233223. doi: 10.1128/mbio.02332-23. Online ahead of print. mBio. 2023. PMID: 37905813 Free PMC article.

Structural insights for selective disruption of Beclin 1 binding to Bcl-2.

Pan YZ, Liang Q, Tomchick DR, De Brabander JK, Rizo J. Pan YZ, et al. Commun Biol. 2023 Oct 24;6(1):1080. doi: 10.1038/s42003-023-05467-w. Commun Biol. 2023. PMID: 37875561 Free PMC article.

Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responses.

Naik SK, McNehlan ME, Mreyoud Y, Kinsella RL, Smirnov A, Chowdhury CS, McKee SR, Dubey N, Woodson R, Kreamalmeyer D, Stallings CL. Naik SK, et al. bioRxiv [Preprint]. 2023 Oct 5:2023.10.03.560720. doi: 10.1101/2023.10.03.560720. bioRxiv. 2023. PMID: 37873329 Free PMC article. Preprint.

Preexisting helminth challenge exacerbates infection and reactivation of gammaherpesvirus in tissue resident macrophages.

Zarek CM, Dende C, Coronado J, Pendse M, Dryden P, Hooper LV, Reese TA. Zarek CM, et al. PLoS Pathog. 2023 Oct 17;19(10):e1011691. doi: 10.1371/journal.ppat.1011691. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37847677 Free PMC article.

Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production.

Xu J, Kong L, Oliver BA, Li B, Creasey EA, Guzman G, Schenone M, Carey KL, Carr SA, Graham DB, Deguine J, Xavier RJ. Xu J, et al. Cell Rep. 2023 Jul 25;42(7):112708. doi: 10.1016/j.celrep.2023.112708. Epub 2023 Jun 30. Cell Rep. 2023. PMID: 37392388 Free PMC article.

Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages.

Kinsella RL, Kimmey JM, Smirnov A, Woodson R, Gaggioli MR, Chavez SM, Kreamalmeyer D, Stallings CL. Kinsella RL, et al. PLoS Biol. 2023 Jun 15;21(6):e3002159. doi: 10.1371/journal.pbio.3002159. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37319285 Free PMC article.

Identification of host regulators of Mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence.

Kalam H, Chou CH, Kadoki M, Graham DB, Deguine J, Hung DT, Xavier RJ. Kalam H, et al. Cell Host Microbe. 2023 Jun 14;31(6):978-992.e5. doi: 10.1016/j.chom.2023.05.009. Epub 2023 Jun 2. Cell Host Microbe. 2023. PMID: 37269834

Activity-based protein profiling - finding general solutions to specific problems.

Cravatt BF. Cravatt BF. Isr J Chem. 2023 Mar;63(3-4):e202300029. doi: 10.1002/ijch.202300029. Epub 2023 Mar 3. Isr J Chem. 2023. PMID: 37206575 Free PMC article.

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