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A proof of concept for structure-based vaccine design targeting RSV in humans.
Science. 2019 Aug 2;365(6452):505-509. doi: 10.1126/science.aav9033.
Science. 2019.
PMID: 31371616
Clinical Trial.
Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial.
Ruckwardt TJ, Morabito KM, Phung E, Crank MC, Costner PJ, Holman LA, Chang LA, Hickman SP, Berkowitz NM, Gordon IJ, Yamshchikov GV, Gaudinski MR, Lin B, Bailer R, Chen M, Ortega-Villa AM, Nguyen T, Kumar A, Schwartz RM, Kueltzo LA, Stein JA, Carlton K, Gall JG, Nason MC, Mascola JR, Chen G, Graham BS; VRC 317 study team.
Ruckwardt TJ, et al.
Lancet Respir Med. 2021 Oct;9(10):1111-1120. doi: 10.1016/S2213-2600(21)00098-9. Epub 2021 Apr 14.
Lancet Respir Med. 2021.
PMID: 33864736
Free PMC article.
Clinical Trial.
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