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The α2B-adrenergic receptor is mutant in cortical myoclonus and epilepsy.
De Fusco M, Vago R, Striano P, Di Bonaventura C, Zara F, Mei D, Kim MS, Muallem S, Chen Y, Wang Q, Guerrini R, Casari G. De Fusco M, et al. Among authors: wang q. Ann Neurol. 2014 Jan;75(1):77-87. doi: 10.1002/ana.24028. Epub 2014 Jan 2. Ann Neurol. 2014. PMID: 24114805 Free PMC article.
Protein kinase A phosphorylation of spinophilin modulates its interaction with the alpha 2A-adrenergic receptor (AR) and alters temporal properties of alpha 2AAR internalization.
Xu J, Chen Y, Lu R, Cottingham C, Jiao K, Wang Q. Xu J, et al. Among authors: wang q. J Biol Chem. 2008 May 23;283(21):14516-23. doi: 10.1074/jbc.M710340200. Epub 2008 Mar 26. J Biol Chem. 2008. PMID: 18367453 Free article.
Spinophilin plays critical roles in regulating trafficking and signaling of the alpha(2)-adrenergic receptor (AR) both in vitro and in vivo (Wang, Q., Zhao, J., Brady, A. E., Feng, J., Allen, P. B., Lefkowitz, R. ...
Spinophilin plays critical roles in regulating trafficking and signaling of the alpha(2)-adrenergic receptor (AR) both in vitro and in vivo …
The amyloid precursor protein modulates α2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment.
Zhang F, Gannon M, Chen Y, Zhou L, Jiao K, Wang Q. Zhang F, et al. Among authors: wang q. FASEB J. 2017 Oct;31(10):4434-4446. doi: 10.1096/fj.201700346R. Epub 2017 Jun 23. FASEB J. 2017. PMID: 28646018 Free PMC article.
Given the important role of alpha(2A)AR in controlling norepinephrine release and response, this novel regulation of alpha(2A)AR by APP may have an impact on modulation of noradrenergic activity and sympathetic tone.-Zhang, F., Gannon, M., Chen, Y., Zhou, L., Jiao, K., Wang …
Given the important role of alpha(2A)AR in controlling norepinephrine release and response, this novel regulation of alpha(2A)AR by APP may …
68,553 results
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