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Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly.
Li H, Fletcher-Etherington A, Hunter LM, Keshri S, Fielding CA, Nightingale K, Ravenhill B, Nobre L, Potts M, Antrobus R, Crump CM, Rubinsztein DC, Stanton RJ, Weekes MP. Li H, et al. Among authors: weekes mp. Cell Host Microbe. 2024 Apr 10;32(4):466-478.e11. doi: 10.1016/j.chom.2024.02.013. Epub 2024 Mar 12. Cell Host Microbe. 2024. PMID: 38479395 Free article.
HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation.
Vlachava VM, Seirafian S, Fielding CA, Kollnberger S, Aicheler RJ, Hughes J, Baker A, Weekes MP, Forbes S, Wilkinson GWG, Wang ECY, Stanton RJ. Vlachava VM, et al. Among authors: weekes mp. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2309077120. doi: 10.1073/pnas.2309077120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011551 Free PMC article.
ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.
Rubina A, Patel M, Nightingale K, Potts M, Fielding CA, Kollnberger S, Lau B, Ladell K, Miners KL, Nichols J, Nobre L, Roberts D, Trinca TM, Twohig JP, Vlahava VM, Davison AJ, Price DA, Tomasec P, Wilkinson GWG, Weekes MP, Stanton RJ, Wang ECY. Rubina A, et al. Among authors: weekes mp. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2303155120. doi: 10.1073/pnas.2303155120. Epub 2023 Aug 10. Proc Natl Acad Sci U S A. 2023. PMID: 37561786 Free PMC article.
122 results