Wester L - Search Results

1

The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.

van Rijssel J, Hoogenboezem M, Wester L, Hordijk PL, Van Buul JD. van Rijssel J, et al. Among authors: wester l. PLoS One. 2012;7(1):e29912. doi: 10.1371/journal.pone.0029912. Epub 2012 Jan 6. PLoS One. 2012. PMID: 22238672 Free PMC article.

2

Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions.

Daniel AE, van der Meer WJ, Wester L, de Waard V, van den Biggelaar M, van Buul JD. Daniel AE, et al. Among authors: wester l. Small GTPases. 2023 Dec;14(1):45-54. doi: 10.1080/21541248.2023.2242166. Small GTPases. 2023. PMID: 37528624 Free PMC article.

3

IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.

Zhang Y, Wester L, He J, Geiger T, Moerkens M, Siddappa R, Helmijr JA, Timmermans MM, Look MP, van Deurzen CHM, Martens JWM, Pont C, de Graauw M, Danen EHJ, Berns EMJJ, Meerman JHN, Jansen MPHM, van de Water B. Zhang Y, et al. Among authors: wester l. Oncogene. 2018 Apr;37(14):1869-1884. doi: 10.1038/s41388-017-0027-9. Epub 2018 Jan 22. Oncogene. 2018. PMID: 29353882

4

Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation.

Moerkens M, Zhang Y, Wester L, van de Water B, Meerman JH. Moerkens M, et al. Among authors: wester l. BMC Cancer. 2014 Apr 23;14:283. doi: 10.1186/1471-2407-14-283. BMC Cancer. 2014. PMID: 24758408 Free PMC article.

5

A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer.

Wester L, Venneker S, Hazenoot M, Pont C, Koedoot E, Timmermans AM, Martens JWM, Jansen MPHM, Kockx CEM, van IJcken WFJ, Meerman JHN, Zhang Y, van de Water B. Wester L, et al. Biochem Pharmacol. 2022 Oct;204:115233. doi: 10.1016/j.bcp.2022.115233. Epub 2022 Aug 28. Biochem Pharmacol. 2022. PMID: 36041543 Free article.

6

A single-copy knockin translating ribosome immunoprecipitation toolkit for tissue-specific profiling of actively translated mRNAs in C. elegans.

Wester LE, Lanjuin A, Bruckisch EHW, Perez-Matos MC, Stine PG, Heintz C, Denzel MS, Mair WB. Wester LE, et al. Cell Rep Methods. 2023 Mar 27;3(3):100433. doi: 10.1016/j.crmeth.2023.100433. eCollection 2023 Mar 27. Cell Rep Methods. 2023. PMID: 37056370 Free PMC article.

7

NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants.

Guerrero GA, Derisbourg MJ, Mayr FA, Wester LE, Giorda M, Dinort JE, Hartman MD, Schilling K, Alonso-De Gennaro MJ, Lu RJ, Benayoun BA, Denzel MS. Guerrero GA, et al. Among authors: wester le. Elife. 2021 Aug 27;10:e53174. doi: 10.7554/eLife.53174. Elife. 2021. PMID: 34448454 Free PMC article.

8

Mutagenesis screen uncovers lifespan extension through integrated stress response inhibition without reduced mRNA translation.

Derisbourg MJ, Wester LE, Baddi R, Denzel MS. Derisbourg MJ, et al. Among authors: wester le. Nat Commun. 2021 Mar 15;12(1):1678. doi: 10.1038/s41467-021-21743-x. Nat Commun. 2021. PMID: 33723245 Free PMC article.

9

Pain drawings as a diagnostic tool for the differentiation between two pain-associated rare diseases (Ehlers-Danlos-Syndrome, Guillain-Barré-Syndrome).

Wester L, Mücke M, Bender TTA, Sellin J, Klawonn F, Conrad R, Szczypien N. Wester L, et al. Orphanet J Rare Dis. 2020 Nov 17;15(1):323. doi: 10.1186/s13023-020-01542-1. Orphanet J Rare Dis. 2020. PMID: 33203450 Free PMC article.

10

5' tRNA halves are highly expressed in the primate hippocampus and might sequence-specifically regulate gene expression.

Jehn J, Treml J, Wulsch S, Ottum B, Erb V, Hewel C, Kooijmans RN, Wester L, Fast I, Rosenkranz D. Jehn J, et al. Among authors: wester l. RNA. 2020 Jun;26(6):694-707. doi: 10.1261/rna.073395.119. Epub 2020 Mar 6. RNA. 2020. PMID: 32144192 Free PMC article.

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