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A disintegrin and metalloprotease 10 is a novel mediator of vascular endothelial growth factor-induced endothelial cell function in angiogenesis and is associated with atherosclerosis.
Donners MM, Wolfs IM, Olieslagers S, Mohammadi-Motahhari Z, Tchaikovski V, Heeneman S, van Buul JD, Caolo V, Molin DG, Post MJ, Waltenberger J. Donners MM, et al. Among authors: wolfs im. Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2188-95. doi: 10.1161/ATVBAHA.110.213124. Epub 2010 Sep 2. Arterioscler Thromb Vasc Biol. 2010. PMID: 20814017
Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.
van der Vorst EP, Jeurissen M, Wolfs IM, Keijbeck A, Theodorou K, Wijnands E, Schurgers L, Weber S, Gijbels MJ, Hamers AA, Dreymueller D, Rose-John S, de Winther MP, Ludwig A, Saftig P, Biessen EA, Donners MM. van der Vorst EP, et al. Among authors: wolfs im. Am J Pathol. 2015 Apr;185(4):1145-55. doi: 10.1016/j.ajpath.2014.11.028. Epub 2015 Feb 7. Am J Pathol. 2015. PMID: 25659879 Free article.
Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression.
Theodorou K, van der Vorst EPC, Gijbels MJ, Wolfs IMJ, Jeurissen M, Theelen TL, Sluimer JC, Wijnands E, Cleutjens JP, Li Y, Jansen Y, Weber C, Ludwig A, Bentzon JF, Bartsch JW, Biessen EAL, Donners MMPC. Theodorou K, et al. Among authors: wolfs imj. Sci Rep. 2017 Sep 15;7(1):11670. doi: 10.1038/s41598-017-10549-x. Sci Rep. 2017. PMID: 28916789 Free PMC article.
High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling.
van der Vorst EPC, Theodorou K, Wu Y, Hoeksema MA, Goossens P, Bursill CA, Aliyev T, Huitema LFA, Tas SW, Wolfs IMJ, Kuijpers MJE, Gijbels MJ, Schalkwijk CG, Koonen DPY, Abdollahi-Roodsaz S, McDaniels K, Wang CC, Leitges M, Lawrence T, Plat J, Van Eck M, Rye KA, Touqui L, de Winther MPJ, Biessen EAL, Donners MMPC. van der Vorst EPC, et al. Among authors: wolfs imj. Cell Metab. 2017 Jan 10;25(1):197-207. doi: 10.1016/j.cmet.2016.10.013. Epub 2016 Nov 17. Cell Metab. 2017. PMID: 27866837 Free article.
Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes.
Stöger JL, Boshuizen MC, Brufau G, Gijbels MJ, Wolfs IM, van der Velden S, Pöttgens CC, Vergouwe MN, Wijnands E, Beckers L, Goossens P, Kerksiek A, Havinga R, Müller W, Lütjohann D, Groen AK, de Winther MP. Stöger JL, et al. Among authors: wolfs im. Thromb Haemost. 2016 Aug 30;116(3):565-77. doi: 10.1160/TH16-01-0043. Epub 2016 Jun 30. Thromb Haemost. 2016. PMID: 27358035
Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.
Medina I, Cougoule C, Drechsler M, Bermudez B, Koenen RR, Sluimer J, Wolfs I, Döring Y, Herias V, Gijbels M, Bot I, de Jager S, Weber C, Cleutjens J, van Berkel TJC, Sikkink KJ, Mócsai A, Maridonneau-Parini I, Soehnlein O, Biessen EAL. Medina I, et al. Circulation. 2015 Aug 11;132(6):490-501. doi: 10.1161/CIRCULATIONAHA.114.012316. Epub 2015 Jun 11. Circulation. 2015. PMID: 26068045 Free PMC article.