Yan R - Search Results

1

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2.

Chi X, Yan R, Zhang J, Zhang G, Zhang Y, Hao M, Zhang Z, Fan P, Dong Y, Yang Y, Chen Z, Guo Y, Zhang J, Li Y, Song X, Chen Y, Xia L, Fu L, Hou L, Xu J, Yu C, Li J, Zhou Q, Chen W. Chi X, et al. Among authors: yan r. Science. 2020 Aug 7;369(6504):650-655. doi: 10.1126/science.abc6952. Epub 2020 Jun 22. Science. 2020. PMID: 32571838 Free PMC article.

2

Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex.

Yan R, Zhao X, Lei J, Zhou Q. Yan R, et al. Nature. 2019 Apr;568(7750):127-130. doi: 10.1038/s41586-019-1011-z. Epub 2019 Mar 13. Nature. 2019. PMID: 30867591

3

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.

Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Yan R, et al. Science. 2020 Mar 27;367(6485):1444-1448. doi: 10.1126/science.abb2762. Epub 2020 Mar 4. Science. 2020. PMID: 32132184 Free PMC article.

4

Cryo-EM structure of the human heteromeric amino acid transporter b^0,+AT-rBAT.

Yan R, Li Y, Shi Y, Zhou J, Lei J, Huang J, Zhou Q. Yan R, et al. Sci Adv. 2020 Apr 15;6(16):eaay6379. doi: 10.1126/sciadv.aay6379. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32494597 Free PMC article.

5

Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.

Guo L, Bi W, Wang X, Xu W, Yan R, Zhang Y, Zhao K, Li Y, Zhang M, Cai X, Jiang S, Xie Y, Zhou Q, Lu L, Dang B. Guo L, et al. Among authors: yan r. Cell Res. 2021 Jan;31(1):98-100. doi: 10.1038/s41422-020-00438-w. Epub 2020 Nov 11. Cell Res. 2021. PMID: 33177651 Free PMC article. No abstract available.

6

Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex.

Yan R, Zhou J, Li Y, Lei J, Zhou Q. Yan R, et al. Cell Discov. 2020 Nov 10;6(1):82. doi: 10.1038/s41421-020-00207-4. Cell Discov. 2020. PMID: 33298890 Free PMC article. No abstract available.

7

A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols.

Yan R, Cao P, Song W, Qian H, Du X, Coates HW, Zhao X, Li Y, Gao S, Gong X, Liu X, Sui J, Lei J, Yang H, Brown AJ, Zhou Q, Yan C, Yan N. Yan R, et al. Among authors: yan n, yan c. Science. 2021 Mar 5;371(6533):eabb2224. doi: 10.1126/science.abb2224. Epub 2021 Jan 14. Science. 2021. PMID: 33446483

8

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.

Yan R, Wang R, Ju B, Yu J, Zhang Y, Liu N, Wang J, Zhang Q, Chen P, Zhou B, Li Y, Shen Y, Zhang S, Tian L, Guo Y, Xia L, Zhong X, Cheng L, Ge X, Zhao J, Wang HW, Wang X, Zhang Z, Zhang L, Zhou Q. Yan R, et al. Cell Res. 2021 May;31(5):517-525. doi: 10.1038/s41422-021-00487-9. Epub 2021 Mar 17. Cell Res. 2021. PMID: 33731853 Free PMC article.

9

Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2.

Yan R, Zhang Y, Li Y, Ye F, Guo Y, Xia L, Zhong X, Chi X, Zhou Q. Yan R, et al. Cell Res. 2021 Jun;31(6):717-719. doi: 10.1038/s41422-021-00490-0. Epub 2021 Mar 18. Cell Res. 2021. PMID: 33737693 Free PMC article. No abstract available.

10

Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.

Yan R, Li Y, Müller J, Zhang Y, Singer S, Xia L, Zhong X, Gertsch J, Altmann KH, Zhou Q. Yan R, et al. Cell Discov. 2021 Mar 23;7(1):16. doi: 10.1038/s41421-021-00247-4. Cell Discov. 2021. PMID: 33758168 Free PMC article.

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