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Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.
Zhang W, Nandakumar N, Shi Y, Manzano M, Smith A, Graham G, Gupta S, Vietsch EE, Laughlin SZ, Wadhwa M, Chetram M, Joshi M, Wang F, Kallakury B, Toretsky J, Wellstein A, Yi C. Zhang W, et al. Among authors: yi c. Sci Signal. 2014 May 6;7(324):ra42. doi: 10.1126/scisignal.2005049. Sci Signal. 2014. PMID: 24803537 Free PMC article.
YAP/TAZ Signaling and Resistance to Cancer Therapy.
Nguyen CDK, Yi C. Nguyen CDK, et al. Among authors: yi c. Trends Cancer. 2019 May;5(5):283-296. doi: 10.1016/j.trecan.2019.02.010. Epub 2019 Mar 27. Trends Cancer. 2019. PMID: 31174841 Free PMC article. Review.
Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH.
Tan M, Mosaoa R, Graham GT, Kasprzyk-Pawelec A, Gadre S, Parasido E, Catalina-Rodriguez O, Foley P, Giaccone G, Cheema A, Kallakury B, Albanese C, Yi C, Avantaggiati ML. Tan M, et al. Among authors: yi c. Cell Death Differ. 2020 Jul;27(7):2143-2157. doi: 10.1038/s41418-020-0491-6. Epub 2020 Jan 20. Cell Death Differ. 2020. PMID: 31959914 Free PMC article.
2,729 results