Yu W - Search Results

1

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

Lenk GM, Jafar-Nejad P, Hill SF, Huffman LD, Smolen CE, Wagnon JL, Petit H, Yu W, Ziobro J, Bhatia K, Parent J, Giger RJ, Rigo F, Meisler MH. Lenk GM, et al. Among authors: yu w. Ann Neurol. 2020 Mar;87(3):339-346. doi: 10.1002/ana.25676. Epub 2020 Feb 6. Ann Neurol. 2020. PMID: 31943325 Free PMC article.

2

Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.

Yu W, Hill SF, Xenakis JG, Pardo-Manuel de Villena F, Wagnon JL, Meisler MH. Yu W, et al. Epilepsia. 2020 Dec;61(12):2847-2856. doi: 10.1111/epi.16741. Epub 2020 Nov 2. Epilepsia. 2020. PMID: 33140451 Free PMC article.

3

Sodium channelopathies in neurodevelopmental disorders.

Meisler MH, Hill SF, Yu W. Meisler MH, et al. Among authors: yu w. Nat Rev Neurosci. 2021 Mar;22(3):152-166. doi: 10.1038/s41583-020-00418-4. Epub 2021 Feb 2. Nat Rev Neurosci. 2021. PMID: 33531663 Free PMC article. Review.

4

Author Correction: Sodium channelopathies in neurodevelopmental disorders.

Meisler MH, Hill SF, Yu W. Meisler MH, et al. Among authors: yu w. Nat Rev Neurosci. 2021 Apr;22(4):256. doi: 10.1038/s41583-021-00449-5. Nat Rev Neurosci. 2021. PMID: 33686192 No abstract available.

5

Spontaneous seizures and elevated seizure susceptibility in response to somatic mutation of sodium channel Scn8a in the mouse.

Yu W, Smolen CE, Hill SF, Meisler MH. Yu W, et al. Hum Mol Genet. 2021 May 29;30(10):902-907. doi: 10.1093/hmg/ddab092. Hum Mol Genet. 2021. PMID: 33822038 Free PMC article.

6

Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy.

Thompson JA, Miralles RM, Wengert ER, Wagley PK, Yu W, Wenker IC, Patel MK. Thompson JA, et al. Among authors: yu w. Epilepsia Open. 2022 Jun;7(2):280-292. doi: 10.1002/epi4.12564. Epub 2022 Feb 8. Epilepsia Open. 2022. PMID: 34826216 Free PMC article.

7

Correction of the hypomorphic Gabra2 splice site variant in mouse strain C57BL/6J modifies the severity of Scn8a encephalopathy.

Yu W, Mulligan MK, Williams RW, Meisler MH. Yu W, et al. HGG Adv. 2021 Oct 8;3(1):100064. doi: 10.1016/j.xhgg.2021.100064. eCollection 2022 Jan 13. HGG Adv. 2021. PMID: 35047853 Free PMC article.

8

Long-Term Downregulation of the Sodium Channel Gene Scn8a Is Therapeutic in Mouse Models of SCN8A Epilepsy.

Hill SF, Yu W, Ziobro J, Chalasani S, Reger F, Meisler MH. Hill SF, et al. Among authors: yu w. Ann Neurol. 2024 Apr;95(4):754-759. doi: 10.1002/ana.26861. Epub 2024 Jan 6. Ann Neurol. 2024. PMID: 38113311

9

Production of Phosphorylated Ric-8A proteins using protein kinase CK2.

Yu W, Yu M, Papasergi-Scott MM, Tall GG. Yu W, et al. Among authors: yu m. Protein Expr Purif. 2019 Feb;154:98-103. doi: 10.1016/j.pep.2018.10.002. Epub 2018 Oct 2. Protein Expr Purif. 2019. PMID: 30290220 Free PMC article.

10

Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A.

Zeng B, Mou TC, Doukov TI, Steiner A, Yu W, Papasergi-Scott M, Tall GG, Hagn F, Sprang SR. Zeng B, et al. Among authors: yu w. Structure. 2019 Jul 2;27(7):1137-1147.e5. doi: 10.1016/j.str.2019.04.013. Epub 2019 May 30. Structure. 2019. PMID: 31155309 Free PMC article.

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