Yuan X - Search Results

1

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition.

Yu J, Yuan X, Chen H, Chaturvedi S, Braunstein EM, Brodsky RA. Yu J, et al. Among authors: yuan x. Blood. 2020 Oct 29;136(18):2080-2089. doi: 10.1182/blood.2020008248. Blood. 2020. PMID: 32877502 Free PMC article.

2

The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria.

Johnston JJ, Gropman AL, Sapp JC, Teer JK, Martin JM, Liu CF, Yuan X, Ye Z, Cheng L, Brodsky RA, Biesecker LG. Johnston JJ, et al. Among authors: yuan x. Am J Hum Genet. 2012 Feb 10;90(2):295-300. doi: 10.1016/j.ajhg.2011.11.031. Epub 2012 Feb 2. Am J Hum Genet. 2012. PMID: 22305531 Free PMC article.

3

Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells.

Yuan X, Braunstein EM, Ye Z, Liu CF, Chen G, Zou J, Cheng L, Brodsky RA. Yuan X, et al. Stem Cells Transl Med. 2013 Nov;2(11):819-29. doi: 10.5966/sctm.2013-0069. Epub 2013 Oct 10. Stem Cells Transl Med. 2013. PMID: 24113066 Free PMC article.

4

Complement blockade with a C1 esterase inhibitor in paroxysmal nocturnal hemoglobinuria.

DeZern AE, Uknis M, Yuan X, Mukhina GL, Varela J, Saye J, Pu J, Brodsky RA. DeZern AE, et al. Among authors: yuan x. Exp Hematol. 2014 Oct;42(10):857-61.e1. doi: 10.1016/j.exphem.2014.06.007. Epub 2014 Jul 14. Exp Hematol. 2014. PMID: 25034232 Free PMC article.

5

Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders.

Soden SE, Saunders CJ, Willig LK, Farrow EG, Smith LD, Petrikin JE, LePichon JB, Miller NA, Thiffault I, Dinwiddie DL, Twist G, Noll A, Heese BA, Zellmer L, Atherton AM, Abdelmoity AT, Safina N, Nyp SS, Zuccarelli B, Larson IA, Modrcin A, Herd S, Creed M, Ye Z, Yuan X, Brodsky RA, Kingsmore SF. Soden SE, et al. Among authors: yuan x. Sci Transl Med. 2014 Dec 3;6(265):265ra168. doi: 10.1126/scitranslmed.3010076. Sci Transl Med. 2014. PMID: 25473036 Free PMC article.

6

Modified Ham test for atypical hemolytic uremic syndrome.

Gavriilaki E, Yuan X, Ye Z, Ambinder AJ, Shanbhag SP, Streiff MB, Kickler TS, Moliterno AR, Sperati CJ, Brodsky RA. Gavriilaki E, et al. Among authors: yuan x. Blood. 2015 Jun 4;125(23):3637-46. doi: 10.1182/blood-2015-02-629683. Epub 2015 Apr 10. Blood. 2015. PMID: 25862562 Free PMC article. Clinical Trial.

7

Direct evidence of complement activation in HELLP syndrome: A link to atypical hemolytic uremic syndrome.

Vaught AJ, Gavriilaki E, Hueppchen N, Blakemore K, Yuan X, Seifert SM, York S, Brodsky RA. Vaught AJ, et al. Among authors: yuan x. Exp Hematol. 2016 May;44(5):390-8. doi: 10.1016/j.exphem.2016.01.005. Epub 2016 Feb 26. Exp Hematol. 2016. PMID: 26921648 Free PMC article.

8

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

Yuan X, Gavriilaki E, Thanassi JA, Yang G, Baines AC, Podos SD, Huang Y, Huang M, Brodsky RA. Yuan X, et al. Haematologica. 2017 Mar;102(3):466-475. doi: 10.3324/haematol.2016.153312. Epub 2016 Nov 3. Haematologica. 2017. PMID: 27810992 Free PMC article.

9

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model.

Yuan X, Li Z, Baines AC, Gavriilaki E, Ye Z, Wen Z, Braunstein EM, Biesecker LG, Cheng L, Dong X, Brodsky RA. Yuan X, et al. PLoS One. 2017 Apr 25;12(4):e0174074. doi: 10.1371/journal.pone.0174074. eCollection 2017. PLoS One. 2017. PMID: 28441409 Free PMC article.

10

Eculizumab cessation in atypical hemolytic uremic syndrome.

Merrill SA, Brittingham ZD, Yuan X, Moliterno AR, Sperati CJ, Brodsky RA. Merrill SA, et al. Among authors: yuan x. Blood. 2017 Jul 20;130(3):368-372. doi: 10.1182/blood-2017-02-770214. Epub 2017 May 1. Blood. 2017. PMID: 28461395 Free PMC article.

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