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Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes: Interim Analysis of 2 Randomized Clinical Trials.
Xia S, Duan K, Zhang Y, Zhao D, Zhang H, Xie Z, Li X, Peng C, Zhang Y, Zhang W, Yang Y, Chen W, Gao X, You W, Wang X, Wang Z, Shi Z, Wang Y, Yang X, Zhang L, Huang L, Wang Q, Lu J, Yang Y, Guo J, Zhou W, Wan X, Wu C, Wang W, Huang S, Du J, Meng Z, Pan A, Yuan Z, Shen S, Guo W, Yang X. Xia S, et al. Among authors: yuan z. JAMA. 2020 Sep 8;324(10):951-960. doi: 10.1001/jama.2020.15543. JAMA. 2020. PMID: 32789505 Free PMC article. Clinical Trial.
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2.
Shi R, Shan C, Duan X, Chen Z, Liu P, Song J, Song T, Bi X, Han C, Wu L, Gao G, Hu X, Zhang Y, Tong Z, Huang W, Liu WJ, Wu G, Zhang B, Wang L, Qi J, Feng H, Wang FS, Wang Q, Gao GF, Yuan Z, Yan J. Shi R, et al. Among authors: yuan z. Nature. 2020 Aug;584(7819):120-124. doi: 10.1038/s41586-020-2381-y. Epub 2020 May 26. Nature. 2020. PMID: 32454512
Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques.
Shan C, Yao YF, Yang XL, Zhou YW, Gao G, Peng Y, Yang L, Hu X, Xiong J, Jiang RD, Zhang HJ, Gao XX, Peng C, Min J, Chen Y, Si HR, Wu J, Zhou P, Wang YY, Wei HP, Pang W, Hu ZF, Lv LB, Zheng YT, Shi ZL, Yuan ZM. Shan C, et al. Cell Res. 2020 Aug;30(8):670-677. doi: 10.1038/s41422-020-0364-z. Epub 2020 Jul 7. Cell Res. 2020. PMID: 32636454 Free PMC article.
An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques.
Feng L, Wang Q, Shan C, Yang C, Feng Y, Wu J, Liu X, Zhou Y, Jiang R, Hu P, Liu X, Zhang F, Li P, Niu X, Liu Y, Zheng X, Luo J, Sun J, Gu Y, Liu B, Xu Y, Li C, Pan W, Zhao J, Ke C, Chen X, Xu T, Zhong N, Guan S, Yuan Z, Chen L. Feng L, et al. Among authors: yuan z. Nat Commun. 2020 Aug 21;11(1):4207. doi: 10.1038/s41467-020-18077-5. Nat Commun. 2020. PMID: 32826924 Free PMC article.
Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys.
Wang S, Peng Y, Wang R, Jiao S, Wang M, Huang W, Shan C, Jiang W, Li Z, Gu C, Chen B, Hu X, Yao Y, Min J, Zhang H, Chen Y, Gao G, Tang P, Li G, Wang A, Wang L, Zhang J, Chen S, Gui X, Yuan Z, Liu D. Wang S, et al. Among authors: yuan z. Nat Commun. 2020 Nov 13;11(1):5752. doi: 10.1038/s41467-020-19568-1. Nat Commun. 2020. PMID: 33188207 Free PMC article.
Biochemical and antigenic characterization of the structural proteins and their post-translational modifications in purified SARS-CoV-2 virions of an inactivated vaccine candidate.
Zhang XY, Guo J, Wan X, Zhou JG, Jin WP, Lu J, Wang WH, Yang AN, Liu DX, Shi ZL, Yuan ZM, Li XG, Meng SL, Duan K, Wang ZJ, Yang XM, Shen S. Zhang XY, et al. Emerg Microbes Infect. 2020 Dec;9(1):2653-2662. doi: 10.1080/22221751.2020.1855945. Emerg Microbes Infect. 2020. PMID: 33232205 Free PMC article.
Low toxicity and high immunogenicity of an inactivated vaccine candidate against COVID-19 in different animal models.
Wang ZJ, Zhang HJ, Lu J, Xu KW, Peng C, Guo J, Gao XX, Wan X, Wang WH, Shan C, Zhang SC, Wu J, Yang AN, Zhu Y, Xiao A, Zhang L, Fu L, Si HR, Cai Q, Yang XL, You L, Zhou YP, Liu J, Pang DQ, Jin WP, Zhang XY, Meng SL, Sun YX, Desselberger U, Wang JZ, Li XG, Duan K, Li CG, Xu M, Shi ZL, Yuan ZM, Yang XM, Shen S. Wang ZJ, et al. Emerg Microbes Infect. 2020 Dec;9(1):2606-2618. doi: 10.1080/22221751.2020.1852059. Emerg Microbes Infect. 2020. PMID: 33241728 Free PMC article.
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