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CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation.
Reyes RM, Deng Y, Zhang D, Ji N, Mukherjee N, Wheeler K, Gupta HB, Padron AS, Kancharla A, Zhang C, Garcia M, Kornepati AVR, Boyman O, Conejo-Garcia JR, Svatek RS, Curiel TJ. Reyes RM, et al. Among authors: zhang c, zhang d. J Immunother Cancer. 2021 Apr;9(4):e002051. doi: 10.1136/jitc-2020-002051. J Immunother Cancer. 2021. PMID: 33849925 Free PMC article.
Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.
Sun X, Wu B, Chiang HC, Deng H, Zhang X, Xiong W, Liu J, Rozeboom AM, Harris BT, Blommaert E, Gomez A, Garcia RE, Zhou Y, Mitra P, Prevost M, Zhang D, Banik D, Isaacs C, Berry D, Lai C, Chaldekas K, Latham PS, Brantner CA, Popratiloff A, Jin VX, Zhang N, Hu Y, Pujana MA, Curiel TJ, An Z, Li R. Sun X, et al. Among authors: zhang n, zhang d, zhang x. Nature. 2021 Nov;599(7886):673-678. doi: 10.1038/s41586-021-04057-2. Epub 2021 Nov 3. Nature. 2021. PMID: 34732895 Free PMC article.
Glucagon-CREB/CRTC2 signaling cascade regulates hepatic BMAL1 protein.
Sun X, Dang F, Zhang D, Yuan Y, Zhang C, Wu Y, Wang Y, Liu Y. Sun X, et al. Among authors: zhang c, zhang d. J Biol Chem. 2015 Jan 23;290(4):2189-97. doi: 10.1074/jbc.M114.612358. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480789 Free PMC article.
AMPK regulates autophagy by phosphorylating BECN1 at threonine 388.
Zhang D, Wang W, Sun X, Xu D, Wang C, Zhang Q, Wang H, Luo W, Chen Y, Chen H, Liu Z. Zhang D, et al. Among authors: zhang q. Autophagy. 2016 Sep;12(9):1447-59. doi: 10.1080/15548627.2016.1185576. Epub 2016 Jun 15. Autophagy. 2016. PMID: 27304906 Free PMC article.
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